2,375 search results for “paddy 1492 1992 disease works” in the Public website
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Prof. Tim Koopmans
Tim Koopmans is one of the great minds in the history of Dutch and European legal scholarship. He taught law as a professor in Leiden and other universities, among which Ghent, Cambridge, Utrecht. He practiced it as a judge in the European Court of Justice and Advocate-General in the Dutch Supreme Court,…
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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Career and development - Working at Leiden University
If you have the ambition to continuously develop and grow in your work, then Leiden University is an attractive employer for you.
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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Life Course
As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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How these young researchers are preparing for their first scientific conference
Three Psychology students will present a poster of their thesis research on Alzheimer’s and dementia at the international conference AAIC Neuroscience Next. ‘I remind myself to recognise - without fear or shame - when I don't know something.’
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Lessons from Rare Diseases
PhD defence
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Leiden University scientists - Working at Leiden University
Nobody is better qualified to tell you what it is like to work at Leiden University than the employees themselves. Watch the videos and meet your future colleagues. They will be happy to share their experiences with you.
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‘Heritage decisions limit our ability to imagine alternative forms of society’
It is difficult to imagine a society other than a hierarchical nation-state. This is in part because we neglect alternative forms from the past, argues archaeologist Lewis Borck in the Journal of Contemporary Archaeology.
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Next Generation ImmunoDermatology project
The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile the immune-mediated inflammatory diseases: i) atopic dermatitis (AD), ii) cutaneous lupus erythematosus (CLE) iii) chronic spontaneous urticaria (CSU) iv) hidradenitis suppurativa (HS) v)…
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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The World of the Fullo. Work, Economy, and Society in Roman Italy
The World of the Fullo takes a detailed look at the fullers, craftsmen who dealt with high-quality garments, of Roman Italy. Analyzing the social and economic worlds in which the fullers lived and worked, it tells the story of their economic circumstances, the way they organized their workshops, the…
- Oort Lecture
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The End of our Third Decade (volume I)
Papers written on the occasion of the 30th anniversary of the Institute of Prehistory, Volume I.
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About
The 21st International Conference on English Historical Linguistics will be held from 7 to 11 June 2021 at Leiden University.
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The Belgian epigraphic and archaeological mission at Shanhur
Update : August 2017 Dr Harco Willems
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Over lokalisme, liefdewerk en lonkend perspectief: Verkenning naar participatie en burgerinitiatief in de Nederlandse archeologie.
Dit rapport maakt deel uit van het project Receptenboek burgerparticipatie in opdracht van de Rijksdienst voor het Cultureel Erfgoed (RCE) en met steun van het Fonds voor Cultuurparticipatie.
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The evolution of shell form in tropical terrestrial microsnails
Promotor: Prof.dr. M. Schilthuizen
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About Leiden University - Working at Leiden University
As far back as 1575, Leiden University researchers have been leaving their mark on the world.
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Why don't drugs make it to the market?
How can we extend the drug residence time to combat diseases more effectively?
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Aging and Immunity
The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.
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Vertebrate automated screening technology (VAST)
How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Chemical biology of sphingolipids: fundamental studies and clinical applications
Overkleeft
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EUR 15 million for excellent archaeological research into the colonisation of the Americas
Corinne Hofman (Professor in Caribbean Archaeology) has been awarded 15 million euro by the EU for her archaeological research on the colonisation of the Americas. She will lead the ‘NEXUS 1492’ project together with colleagues Davies (VU), Brandes (Konstanz) and Willems (Leiden).
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CoSTREAM: Understanding Stroke and Alzheimer
The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Rational Design of Athero-Protective Vaccines; Novel Vaccine Formulations and Alternative Routes of Administration
Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.
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Dr. Kiefte-de Jong and Dr. Bosker, Assistant Professors at LUC, both awarded LUF Awards
Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).
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The Hague International Space Resources Governance Working Group
The development of space resource activities is happening now. In the absence of a clear framework to govern these activities, there is a need to examine the concepts that are being discussed in order to ensure that they meet existing treaty obligations regarding on-orbit operations and space resource…
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Translations of Greek Tragedy in the Work of Ezra Pound
Turning the tables on the misconception that Ezra Pound knew little Greek, this volume looks at his work translating Greek tragedy and considers how influential this was for his later writing.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Osteoarchaeologist Maia Casna interviewed on a podcast
PhD candidate Maia Casna was a guest on the new episode of the Wetenschappelijke Wezens podcast. In it, Maia discusses her research on urbanisation and respiratory diseases while uncovering the intricacies of studying the human past and bones.
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Nose of E. coli zips open and shut
PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
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Attacking tuberculosis bacteria: an interview with Mónica Varela
This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.
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Cell architecture and pathways for parallel secretion in the filamentous fungus Aspergillus niger
Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
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Plant ageing, rejuvenation and life history strategy
What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?
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IBL Spotlight - Development and Disease
Lecture
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Law and peace in the work of Hans Kelsen
Law and peace in the work of Hans Kelsen. A re-evaluation of Kelsen’s legal philosophy: legal pacifism as tacit meaning of his Pure Theory of Law
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Data Analytics and Management
Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Reports
Overview of the CML reports
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Older publications
Overview of the publications of the department of Environmental Biology (1972-2015)
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Programme structure
The master's specialisation Health and Medical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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'No, I don't find my work creepy'
Archaeologist Hayley Mickleburgh has already appeared in the Dutch papers a few times already due to her unusual work: the study of decomposing bodies. She studied at Leiden University, where she is now a researcher.
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Research with animals
At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.