A job thanks to COVID—something not many people can claim. But PhD candidate Vera Arntzen can. Over the past four years, she has mapped two crucial characteristics of SARS-CoV-2 infections. Thanks to her research, experts can now make well-informed decisions on matters like quarantine duration, which…

We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.

Lecture

At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.

A central and much debated topic in the study of language acquisition concerns the nature of the learning mechanisms that are required. Are the computational and learning mechanisms that guide learning about language structure special and specific to language or humans?

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

An e-coaching programme helps people with chronic kidney disease, particularly in areas that patients themselves want to work on. ‘A healthy lifestyle is important for patients with kidney disease: it can slow down the loss of kidney function and there will be fewer complications,’ Katja Cardol explains…

A vitamin D deficiency is often associated with smoggy English industrial cities during the Industrial Revolution, but research carried out on skeletons now suggests that the ‘English disease’ was also prevalent in rural areas of the Netherlands. Doctoral defence on 29 January.

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

We present our plans on five work areas: Students, Inclusive Education, Staff, Research, and Accessible and Inclusive Learning and Working Environment. For each work area, we explain which topics are relevant and what policy measures we (plan to) take.

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

How can zebrafish research help understanding human diseases?

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

In the MS Cognitietour, psychologists and neuroscientists from Leiden University discuss the latest scientific knowledge with MS patients and their loved ones. This leads to insights: 'One lady told how much stress she felt from all those caregivers around her bed.'

We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…

What is the role of auxin in the initiation and process of somatic embryogenesis?

Supervisor: Lizi Xia

What does it mean to eat healthily and responsibly? This question is gaining a new urgency now that in many countries undernourishment is being overtaken by diseases of affluence, such as obesity, and we are also becoming more aware of the environmental impact of our eating habits. It’s time to take…

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

On 18 May 2022 Lan-Yi Yang successfully defended a doctoral thesis and graduated.

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

Health psychologist Andrea Evers has won the Stevin Prize – alongside the Spinoza Prize, the highest scientific award in the Netherlands. Evers: 'It’s also a prize for our whole team and our many contacts within and outside the University.’

This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?

The Grotius Centre Working Paper Series is an occasional series through which researchers in the Grotius Centre can publish the unedited versions of manuscripts that have been accepted for publication by journals and books.

Heart failure is a major health care problem with high mortality.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

If you’re experiencing too much work pressure, talk about it to your colleagues and your manager. This is the only way we can jointly work towards a solution. How do you raise the issue of work pressure? And what can you do to prevent work pressure from getting out of hand?

The document below contains the faculty D&I work plan drawn up for Leiden Law School. This work plan is linked to the University work plan of the D&I Expertise Office.

Many students want to find themselves a job during their studies, to help cover their expenses for example, or they might want to stay and work in the Netherlands after graduating. While there are certainly possibilities in both these areas, you’ll need to bear in mind that there are also restrictio…

Are you interested in one of our vacancies? To get to know each other well, we follow a number of steps in the application process.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

Want to work at a top university, with excellent career opportunities? Discover the opportunities at Leiden University.

We strive for FGGA staff to feel sufficiently challenged and recognized with an assigned workload that is realistic within their working hours. Besides that, staff should be transparently and correctly informed about their personal career perspectives and growth opportunities within the faculty / un…