Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.

A theoretical project on the insights gained by human (including infant), nonhuman animal and computational studies on artificial grammar learning; identifying the critical questions for future research by developing novel experimental and computational approaches to address these issues.

Starting as an MP during the Covid-19 pandemic and after the recent ‘role elsewhere’ debacle during the coalition talks for a new Dutch government, alumna Mariëlle is looking forward to making a real contribution in society.

An international team of researchers, involving members from the ERC Synergy project NEXUS 1492 based at the Leiden University, the Universities of Oklahoma, Copenhagen and York reveal challenges when studying ancient microbiomes in a recent issue of Scientific Reports.

Associate Professor of Physical Geography Paul Hudson at Leiden University College was interviewed by TIME Magazine on the Mississippi floods that have been harassing the United States this year.

Professor Paul van der Heijden (international labour law Leiden University) has been appointed the honorary Marcel Storme chair at the University of Ghent. The Marcel Storme chair is a rotating professorship at the law faculty of the University of Ghent which according to the regulations is solely…

Alireza Mashaghi and his research team have created a new framework to understand shapes of proteins and DNA. With this framework, many diseases can be understood better.

Every year, an NWO PhD in the Humanities grant is awarded to a prospective PhD candidate at the Faculty of Archaeology. This year, the grant went to Maia Casna, enabling her to study respiratory disease in the past. ‘My hypothesis is that the rapid formation of cities in the medieval Netherlands, must…

Mapping of bacterial genomes to combat infectious diseases

Over the past few hundreds of years, the world has changed radically. However, cultural stereotypes from the 17th century are still alive and well today, and even academic researchers sometimes use terms coined centuries ago. Why do they do that? Herman Paul, Professor of the History of the Humanities,…

This research project is an integral part of its mother-programme NEXUS1492 ERC Synergy Project directed by Prof. Corinne Hofman. Overarchingly, it aims at understanding and bridging from the archaeological perspective the late pre-colonial and early colonial history of the Southeastern Caribbean macroregion…

Can thrips resistance in strawberry be explained based on secondary metabolite profiles and plant morphological traits?

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

How is vegetative development regulated in plants and how does this affect a plant’s life history strategy?

Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.

Fake news about ‘patient zero’ and hyperbolic headlines warning about the ‘yellow peril.’ Leiden researchers have spotted fake news galore about coronavirus as well as racial stereotypes about the Chinese. How harmful is this?

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

On 9 September, in the presence of King Willem Alexander, Secretary of State Sander Dekker presented the Spinoza Prize to four researchers, including two researchers from Leiden: archaeologist Corinne Hofman and physicist Dirk Bouwmeester. In the Nieuwe Kerk in The Hague, they unveiled their plans for…

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

A thousand-year-old tooth has provided genetic evidence that the so-called

A new study published in Archaeometry describes the unexpected results obtained from analyses of five human teeth discovered in a ritual cache at an enslaved African plantation site on the island of Saba in the Caribbean.

The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Earlier this year, the public voted environmental scientist Paul Behrens Discoverer of the Year 2018. Behrens is an interdisciplinary scientist who wants to understand our impact on the planet. ‘Unfortunately, we are not doing enough. Huge changes are underway and we’re running out of time to avoid…

George Floyd's death still leads to fierce protests against police violence and racism on a daily basis in the United States and abroad. We asked Paul Wouters how he experiences these developments and what this will mean for our faculty.

Students of the Bachelor Honours Class 'Strategies of Resilience' are exposed to a unique educational experience. Through philosophical insights and creative exercises, participants explore what it means to be resilient. ‘I really feel like it helps you develop as a person.’

How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?

How can Staphylococcus aureus bacteria subvert the host immune system?

How can cell wall engineering approaches be used to improve streptomycetes for industry to make new antibiotics?

Female and male songbirds sing equally elaborate songs in some species, but in others, females do not sing like males or not at all. How did such pronounced differences in male and female communication evolve?

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

TRANSAUTOPHAGY is a European COST action to promote multidisciplinary research on autophagy and translation of knowledge to applications.

Since August 2017, dr. Sarah Schrader is working at the Faculty of Archaeology in the department of Archaeological Sciences. Her expertise is human osteology with a specific focus on the bio-archaeological reconstruction of daily activities. Recently she took over the management of the Osteoarchaeology…

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

A multiple isotope approach to human-animal dynamics in the Lesser Antilles across the historical divide

Dynamics of material, social and ideological relationships in the pre-Columbian insular Caribbean

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

When parking in reverse, your car skids off just a little, hitting the wall of the parking garage. On the car dashboard, a warning light immediately starts blinking. This technique from new cars can also be used for another purpose, namely in the treatment of Parkinson's disease patients.

Starting as an MP during the Covid-19 pandemic and after the recent ‘role elsewhere’ debacle during the coalition talks for a new Dutch government, alumna Mariëlle is looking forward to making a real contribution in society.

Alireza Mashaghi from the Leiden Academic Centre for Drug Research (LACDR) will use state-of-the-art technology to investigate proteins that play a role in muscular dystrophy. His goal is to provide new insights for designing novel therapeutic strategies in the future. To accomplish this, Mashaghi receives…

Minister Grapperhaus wants to use intelligence services in the investigation of drug crime. There are many doubts about this wish in the intelligence world. Paul Abels, Professor by Special Appointment Governance of Intelligence and Security Services at the Institute of Security and Global Affairs (ISGA),…

In recent months, the Dutch Islamic Haga Lyceum has increasingly come under the suspicion. The school is suspected of spreading a state-threatening version of the Salafist doctrine. This information came from the Dutch Intelligence and Security Service (AIVD).

Archaeologist Hayley Mickleburgh has already appeared in the Dutch papers a few times already due to her unusual work: the study of decomposing bodies. She studied at Leiden University, where she is now a researcher.