Can drug screening for tuberculosis treatment be made more efficient?

What is the function of the insect serosa?

Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?

We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?

Promotor: F.S. de Boer Co-promotor: P. T. de Gouw

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

During the Faculty Staff Meeting of August 28th, Corinne Hofman spoke about her time on the Faculty Board. “I look back on a rich decade in which I have seen the Faculty, and the University as a whole, change at a rapid pace.”

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Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…

Is polder rice a feasible circular alternative to cows on peat soil? In May, an experimental trial began, with researchers from Leiden University and Wageningen University & Research (WUR) planting around 3,000 rice plants at the Polderlab near Leiden. The researchers aimed to test rice as a middle…

The Working Paper Series reflects the yet-to-be published work of eLaw researchers and the unedited versions of manuscripts that have been accepted for publication by journals and books.

How does governing work today, and how does society handle pressing challenges in ways that are democratic, effective, fair, peaceful, and sustainable?

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The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Floris Keehnen has been awarded the Volkskrant thesis prize 2012 for his MA thesis entitled:

We examine how soil inoculation influences aboveground organisms (i) directly, and indirectly via (ii) its effects on plant chemistry or volatile emission, or via (iii) mediating the effects of belowground pathogens on aboveground organisms via the shared plant.

Which immune mechanisms are involved in host defense against Staphylococcal infection?

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

Welcome to your starting point for collaboration with the Leiden Learning & Innovation Centre. Whether you're part of Leiden University or an external organization, this page will direct you to the right pages and contacts, ensuring a smooth beginning to our collaboration.

Heart patients who maintain a healthy lifestyle can start earning discounts at shops or for trips out. The Tergooi Hospital is the first in the Netherlands to introduce this unique method that was co-developed by the research group headed by Professor of Health Psychology Andrea Evers and the Leiden…

Professors Simcha Jong (Leiden University) and Rifat Atun (Harvard University) convened an exploratory seminar to discuss challenges for health systems in realising the potential of precision medicine at Harvard University’s Radcliffe Institute for Advanced Studies in Cambridge, MA on 17 April 2017.

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How do young people pursue their interests in and across multiple contexts while participating in tailor-made programs in vocational education and training (VET) and social enterprises to regain perspective in school and work?

Leiden University has locations in both Leiden and The Hague.

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

Utilization of plant-originated products as new antibiotics

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

Leiden University publishes an overview of the ancillary positions of its professors.

The Secret Life of Art Works. Exploring the Boundaries between Art and Life is the first collection of essays to present case studies from the visual arts, architecture, sculpture and numismatics, and to engage critically with theoretical perspectives from art history, psychology, aesthetics and ant…

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On 28 June 2018, Qiuyin Hu defended his doctoral thesis 'Regulating Working Conditions in Times of Globalization'. The doctoral research was supervised by Prof.dr. G.J.J. Heerma van Voss and Prof. dr. B. Barentsen.

With this thesis the PhD-candidate aims to enrich the body of evidence concerning the relation between stress and health, and the mediating role of (un)conscious perseverative cognitions, which is captured in the extended perseverative cognition hypothesis.

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

How do plant defense genes get activated?

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On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

Majuka Tanabe defended her thesis on 17 June 2015