Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish

The Netherlands Organisation for Scientific Research (NWO) has made a subsidy of 17 million euros available to further develop a Netherlands network for electron microscopy (NEMI). The network comprises five UMCs and eight universities, with Utrecht in the coordinating role. From Leiden, the Institute…

Leiden Biology student Lukas Kiefer has won the Unilever Research Prize 2018 for his research into efficient production of a new antibiotic. Kiefer: ‘I want to make biological medicines available to people in need.'

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

Biological chemist Nathaniel Martin is going to test an alternative antibiotic that can combat common resistant bacteria such as MRSA. For this purpose, he will receive 350,000 euros from the NWO's NACTAR programme. ‘We want to know how safe and effective our antibiotic is in a realistic situation.’

On 5 November 2021, Professor Michiel van de Sande of the Department of Orthopedics in the Leiden University Medical Centre (LUMC) delivered his inaugural lecture ‘The Art of Doing and Doing Nothing’. Van de Sande used the opportunity to explore both physical and philosophical aspects of co-decision…

The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…

Asexual procreation in female wasps leads to an accumulation of genetic mutations, and the shrivelling of their sex organ. Leiden biologist Ken Kraaijeveld published this discovery in Evolution. His research is one of the first experimental studies into the consequences of asexual procreation.

On 10 March 2017, Professor Karel Luyben (TU Delft) welcomed the ‘Metabolomics GO FAIR Implementation Network’ as community initiative to start the European Open Science Cloud. The network aims to implement the FAIR data principles in the field of metabolomics in Europe.

The transatlantic slave trade between the 15th and 19th centuries represents one of the most traumatic chapters in history and is now widely recognised as a crime against humanity. EUROTAST is a new European-funded research network that will bring together an unprecedented range of researchers to examine…

The ERC Council has awarded Starting Grants to five promising Leiden researchers. With an impressive three laureates, the Faculty of Social and Behavioural Sciences has done particularly well. The fourth grant goes to the LUMC and the fifth to the Faculty of Governance and Global Affairs.

Have you considered including the Leiden University Fund in your will?

PhD candidate Marc Baggelaar of the Leiden Institute of Chemistry (LIC) graduated cum laude on Thursday 6 April. His thesis on the endocannabinoid system in the brain is very comprehensive and of high quality, according to the jury. ‘A very talented young scientist, that definitely belongs to the top…

Psychology teacher of the year is Anouk van der Weiden. The master thesis awards are for Irina Verhülsdonk and Christel Klootwijk. Eliška Procházková receives the PhD publication prize; Katja Cardol and Judith Tommel the PhD wild card: the Open Science Award. Conny Binnendijk earns the OBP prize and…

Care robots, medical treatments, deepfakes and self-driving cars all with the aid of artificial intelligence (AI). The BrAInpower exhibition at Rijksmuseum Boerhaave shows spectacular applications of AI and explains how it can make such huge leaps. Bas Haring, Professor of Public Understanding of Science,…

What chemicals do plants have available, and what happens if they use them when faced with bacteria or fungi? That is what PhD candidate Luis Salomé Abarca is keen to learn. He studies plants’ survival and their use of chemical components in communication and defence. Salomé Abarca works at the Natural…

This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB

How do practice and theory reinforce one another in neuroscience? Professor Birte Forstmann’s inaugural lecture on 2 October will be about building interdisciplinary bridges between cognitive neuroscience and cognitive models. Her approach may lead to brain research with fewer side-effects for patie…

Research by bioarchaeologists from Leiden and Canada has shown that 19th-century Dutch farmers regularly had bone defects. These may have been caused by wearing clogs. Publication in the International Journal of Paleopathology.

Cooperation is the solution to international problems, demonstrated the final seminar of the Master Honours Class ‘Smart Regional Integration’ – even when it is sometimes easier said than done. “You can see the students struggle with that.”

How do practice and theory reinforce one another in neuroscience? Professor Birte Forstmann’s inaugural lecture on 2 October will be about building interdisciplinary bridges between cognitive neuroscience and cognitive models. Her approach may lead to brain research with fewer side-effects for patie…

A new mathematical model may explain how body cells get their shapes and what makes them move within a tissue. The model provides fundamental knowledge for applications in tissue engineering, amongst other things. Publication in open-access journal iScience.

Using photosynthesis to generate energy, or using enzymes to effectively produce biofuel; Leiden chemists Huub de Groot en Hermen Overkleeft have both obtained an NWO TOP funding for their pioneering research. With the money they can take on new PhD students.

What do gender identity and digital technology have to do with each other? Together they are the subject of research at Leiden University. Researchers Tessa Verhoef and Eduard Fosch-Villaronga of the faculties of Mathematics and Natural Sciences and Law will investigate the interaction between artificial…

Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.

On Sunday 29 October the annual open day of the Old Observatory will take place. During this day, people can visit the Old Observatory for free and enjoy the historic building.

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

Of this year’s four NWO Spinoza Prizes, two have been awarded to Leiden researchers. On 12 September, Eveline Crone and Michel Orrit received their prizes, the highest scientific award in the Netherlands. The Spinoza Prize carries an award of 2.5 million euros.

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

A consortium of international researchers comes with a unique solution to the energy problem. By mimicking photosynthesis, they aim to produce sustainable fuels out of sunlight, water, and CO2. Their secret? ‘Soap bubbles’, says Leiden chemist Sylvestre Bonnet, who is part of the consortium.

Are Weyl particles the ideal conductors? Do cells without a cell wall play a role in chronic Tuberculosis infections? Carlo Beenakker and Dennis Claessen want to answer these questions. They both received a KLEIN grant from the NWO. With these grants, NWO wants to stimulate innovative, fundamental r…

The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…

Bacteria and fungi on organic dairy farms are significantly different from those on conventional farms. That was discovered by postdoc researcher Sofia Gomes and her supervisors Nadia Soudzilovskaia and Peter van Bodegom in collaboration with the Louis Bolk Institute and Naturalis Biodiversity Centre.…

Each year a staggering 18 billion chickens, turkeys, pigs, sheep, goats, and cows either die or are killed without making it onto someone's plate. Environmental scientists Juliane Klaura, Laura Scherer, and Gerard Breeman were the first to calculate this number on a global scale. 'Reducing these numbers…

Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.

How do you manage a crisis? This is what Professor of Crisis Governance Sanneke Kuipers will address in her inaugural lecture.

No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

The Horizon 2020 project ImageInLife has started on 1 January, followed by a kick-off meeting at the coordinating University of Montpellier at the end this month. This Marie Skłodowska-Curie training network brings together European groups that work on the imaging of vertebrates and offers fourteen…

Researchers have spent years looking for the ‘missing link’ between wolves and dogs. But many of the domesticated dogs that had been found prove to have been wolves after all. This is what vet and archaeologist Luc Janssens says in his dissertation. PhD defence on 27 June.

Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.

Lotje Zuur sometimes has to perform disfiguring operations. As a head and neck surgeon, she removes parts of the mouth, throat or face of people with cancer. Now a promising treatment may make such operations unnecessary. What would this mean for patients? This is what her inaugural speech on 19 September…

Globally, the number of deaths from infections is on the rise as more bacteria become resistant to antibiotics. New classes are desperately needed. A promising resistance inhibitor is now being developed by the research group of Nathaniel Martin, Professor of Biological Chemistry. Inaugural speech on…

From documentaries, zines and exhibitions to a video installation. Students of the Visual Ethnography master's programme pulled out all the stops to finish their studies in a fantastic way. For one year, the 23 students worked on their own multimedia projects. The screening of the projects took place…

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

Astronomical observations in Chile, research into native heritage or the treatment of eye diseases in Brazil - Leiden is researching a large number and a wide variety of different topics in Latin America and the Caribbean. Researchers and representatives from 20 countries met on 11 May in Leiden to…

Master's students of Vitality & Ageing work together with older individuals in the so-called ‘Living Lab’ to combat loneliness. You can watch four brief video’s that show their creative solutions for the course ‘the older individual’ that is coordinated by health psychologist Sandra van Dijk and former…