Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…

Of this year’s four NWO Spinoza Prizes, two have been awarded to Leiden researchers. On 12 September, Eveline Crone and Michel Orrit received their prizes, the highest scientific award in the Netherlands. The Spinoza Prize carries an award of 2.5 million euros.

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

What do gender identity and digital technology have to do with each other? Together they are the subject of research at Leiden University. Researchers Tessa Verhoef and Eduard Fosch-Villaronga of the faculties of Mathematics and Natural Sciences and Law will investigate the interaction between artificial…

Eduard Fosch-Villaronga and Bart Custers from eLaw - Center for Law and Digital Technologies wrote an article on Fair Medicine and AI highlighting that AI for biomedical research and healthcare should be beneficent and equitable for everyone.

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

For a long time, even many researchers thought that guide dogs were a relatively modern invention. An accidental encounter with archival material showed university lecturer Krista Milne that guide dogs helped their blind owners as far back as the Middle Ages. Milne now has received an NWO XS grant to…

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Lotje Zuur sometimes has to perform disfiguring operations. As a head and neck surgeon, she removes parts of the mouth, throat or face of people with cancer. Now a promising treatment may make such operations unnecessary. What would this mean for patients? This is what her inaugural speech on 19 September…

No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…

Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.

The Horizon 2020 project ImageInLife has started on 1 January, followed by a kick-off meeting at the coordinating University of Montpellier at the end this month. This Marie Skłodowska-Curie training network brings together European groups that work on the imaging of vertebrates and offers fourteen…

Researchers have spent years looking for the ‘missing link’ between wolves and dogs. But many of the domesticated dogs that had been found prove to have been wolves after all. This is what vet and archaeologist Luc Janssens says in his dissertation. PhD defence on 27 June.

Globally, the number of deaths from infections is on the rise as more bacteria become resistant to antibiotics. New classes are desperately needed. A promising resistance inhibitor is now being developed by the research group of Nathaniel Martin, Professor of Biological Chemistry. Inaugural speech on…

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…

Technological innovations such as home dialysis could significantly improve the quality of life and health of kidney patients. Professor Joris Rotmans therefore wants to continue pushing for new medical technology, as he will explain in his inaugural lecture on 24 March.

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

A month ago it was Marc Baggelaar, and now Hans Kistemaker too has obtained his PhD cum laude at the Leiden Institute for Chemistry (LIC). ‘He has made ground-breaking contributions to the world of protein modification,’ says PhD supervisor Gijs van der Marel. Kistemaker obtained his PhD on 11 May…

From documentaries, zines and exhibitions to a video installation. Students of the Visual Ethnography master's programme pulled out all the stops to finish their studies in a fantastic way. For one year, the 23 students worked on their own multimedia projects. The screening of the projects took place…

Master's students of Vitality & Ageing work together with older individuals in the so-called ‘Living Lab’ to combat loneliness. You can watch four brief video’s that show their creative solutions for the course ‘the older individual’ that is coordinated by health psychologist Sandra van Dijk and former…

On Thursday 9 November, Leiden University organized its annual Physics Ladies Day for female high school students. To mark this festive day, we put the spotlight on two female researchers, who talk about their experiences in physics.

Using photosynthesis to generate energy, or using enzymes to effectively produce biofuel; Leiden chemists Huub de Groot en Hermen Overkleeft have both obtained an NWO TOP funding for their pioneering research. With the money they can take on new PhD students.

Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).

Medical research is often exaggerated in the news. Medical journalists are not the only ones guilty of such sloppiness; results are also often exaggerated in academic press releases. This was the conclusion of a study by researchers from Leiden University Medical Center (LUMC) and Leiden University,…

For the first time, research has been conducted on how the health of detained persons prior to their detention differs from that of non-detainees and to what extent health problems change over the period: from before and after their detention.

In a publication in Science, Noam Zelcer from the Division of Biopharmaceutics describes a previously unrecognized pathway to regulate LDL-cholesterol levels. He is also able to modulate this pathway. This opens the possibility for complementing and improving the efficacy of statins: A class of drugs…

The certificate award ceremony of the Honours College took place in the Hooglandse Church in Leiden on Tuesday 21 November. During the ceremony, two students shared their experiences with honours education while Vice-Rector Hester Bijl addressed the students.

Jos F. Brosschot has been appointed as a professor by special appointment on the chair ‘psychophysiological mechanisms of stress in daily life’. This chair has been created by the Foundation for Research into Psychosocial Stress.

Thanks in part to the persistence of a Leiden research group, cancer could be detected in the near future with just a single drop of blood. Not only can the diagnosis be determined at an earlier stage, but the blood test is also cheap, fast and patient friendly. The first results of this method seem…

This year, two Leiden master students will be awarded a KNMP Student Award. Both Wisse van Os and Jip Linthorst will receive 1,000 euros from the Royal Dutch Pharmacists Association (KNMP) as a reward for their excellent study results, motivation and commitment.

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.

‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…

PhD-student Maia has received multiple awards regarding her research on the impact of tobacco on the respiratory health of past Dutch populations.

With a 'Kiem grant' of up to €10,000, Leiden University stimulates initiatives in research and education where diverse fields of study meet. This interdisciplinary approach helps solve complex issues.

Three international research projects involving Leiden University researchers will receive funding from the Una Europa university alliance.

2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…

Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.

Discover budding creators, artists and researchers at the Night of Discoveries art and knowledge festival. And many researchers from Leiden University are taking part.

Pancras Hogendoorn bade farewell as Dean of Medicine and Vice-Chairman of the LUMC Board of Directors with a symposium at the LUMC.

On November 1st, 2024, professor Johan Kuiper will retire and be appointed as emeritus professor at Leiden University. Since November 2008, Johan Kuiper was professor of Therapeutic Immunomodulation in the division of, at that time, Biopharmaceutics (which later on became the division of BioTherapeutics)…

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