Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

An overview of the research at the Biologics Formulation group

The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…

Promotor: Prof.dr. S. Haring

How to understand the simultaneously dis- and reappearance of letters in contemporary culture, and how does this Neo-Epistolarity relate to media-technological change?

Bernard Bernards examines constraints on innovation by focusing on cognitive uncertainty as a personal state that may affect innovative work behavior.

To deliver a Virtual Sensor tool optimised to exploit the synergy between Sentinels 2 and 3 to allow the consistent retrieval of land surface parameters (Albedo, LAI, and LST); To extend the existing capabilities of land EO data assimilation tools to add capacity to handle data in the thermal domain…

How are digital risk-profiles developed and used in practice?

This paper written by Vydra and Kantorowicz answers the research question ‘What policy-relevant information does Twitter contain?’ as well as the research question ‘How does this information change between a period of normalcy and a period of crisis?’

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Influenza CD8(+) T-cell epitopes are conserved amongst influenza strains and can be recognized by influenza-specific cytotoxic T-cells (CTLs), which can rapidly clear infected cells. An influenza peptide vaccine that elicits these CTLs would therefore be an alternative to current influenza vaccines,…

Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?

William Lippert investigates the effect of delegation to an agreement executor on success of conventional arms control agreements in Europe.

On 22 June, Anneke Koning defended the thesis 'Return to sender: a multi-method study of guardianship against transnational sexual exploitation of children'. The doctoral research was supervised by Joanne van der Leun, Masja van Meeteren and Johan van Wilsem.

List of Kloosterman professors

Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…

African oral literatures, new media and technologies: challenges for research and documentation

An overview of awards and prizes granted to our staff and students in 2020, as well as special appointments at Leiden University and other institutions.

Amerindian settlement patterns and early colonial cartography in Northern Hispaniola

Leiden University professor of Science-Based Business Simcha Jong Kon Chin has been awarded an ERC Consolidator Grant.

How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Do natural soundscapes affect migratory decisions of fishes moving up and down rivers and is this process disturbed by vessel sounds?

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

Research at the SBC group is comprised of the following research themes:

What can languages spoken in the Lesser Sunda Islands today tell us about the histories of its various population groups?

Edward Elgar

Development of micro-scale analytical tools to be used to address relevant biomedical questions in the field of neuroscience, and other application areas intrinsically dealing with small sample amounts.

The programme of the 3rd International Workshop on Klinefelter Syndrome, Trisomy X, and XYY. International Workshop theme: 'A life-course perspective'

Isotopes on exoplanets, a more efficient memory for data centres or new molecules that work against the Zika virus and HIV. Which PhD candidate has written the most impressive dissertation of 2023? The jury of the C.J. Kok Jury Award faces the challenging task of deciding that. Meet the nominees of…

Do sustainability values play a role in motivating people to act for biodiversity in successful projects and in successful leadership action? And how could these values be incorporated in current economic valuation methods?

Promotor: H.J.M. de Groot

Ancient Greek was spoken in a large number of different dialects. Although we do not find direct evidence for syllabic liquids in any of our sources, comparative evidence shows that these sounds must have been present in Proto-Greek, and that they were retained until comparatively recently in the prehistory…

What are the possibilities of converting biowaste streams into value added products? What current and future technologies will enable this transition with minimal environmental and economic costs? The researchers in H2 steel project will enable the transition of sewage sludge into green hydrogen, steel…

Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.

A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…

Overview of the publications of the department of Environmental Biology (1972-2015)

The map application includes information from old and new buildings archaeological projects. This makes it possible to investigate whether water facilities (wells, cisterns) and waste facilities (cesspits, sewers) were the privilege of Leiden’s wealthy elite in the late 16th and 17th centuries or whether…

The NVIC has published a series of scholarly publications in Arabic and several European languages.

A novel in vivo model system for studies on glucocorticoid resistance

An overview of the research at the Cancer Dug Target Discovery group.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

A workshop (Cairo, Egypt, 14-15 September 2018) organized by the Netherlands-Flemish Institute in Cairo with support from “DICIS” / Digital Cinema Studies https://www.digitalcinemastudies.com/

Across Thailand, Indonesia and Sri Lanka there is an urgent need for appropriate educational programmes that develop skills in data science and artificial intelligence. European and Asian experts in Artificial Intelligence education came to Leiden University from 11 to 15 November to agree on a novel…

Lecture

Three novelists have won the first Leiden University Peter van Straaten Psychology Prizes: Esther Gerritsen, Yvonne Keuls, and Marieke Lucas Rijneveld. This is a prize for Dutch writers whose novels shed light on psychological problems and disorders. The prizes will be awarded on January 16.

The English edition of Rijpkema’s Weerbare democratie is published in Routledge’s Extremism and Democracy series, one of the leading series in the field, edited by Roger Eatwell and Matthew Goodwin.

What do a novel anti-ageing ingredient for cosmetics and a new type of chicken feed have in common? They were both produced using a new solvent developed by Leiden biologists in 2011. The medium is neither solid nor liquid, and the industry is now starting to see it’s many possibilities.

Researchers from Leiden University will develop a new approach to study the biomarkers of Alzeimer’s disease. This approach focusses on the molecular messengers of the cells. The project, led by Thomas Hankemeier and coordinated by Yuliya Shakalisava (Leiden Academic Centre for Drug Research, LACDR),…