1,035 search results for “als” in the Public website
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Maar zo bedoelde ik het niet!
Aan de hand van bekende en minder bekende voorbeelden uit de wereld van politiek en media laat dit boek zien hoe je strategisch gebruik én misbruik kunt maken van taal.
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Profile 1. State formation in medieval Frisia
Politically speaking, the Frisian coastal area constitutes a special case in late medieval Europe since it was not subject to an overlord as it withstood feudalization in the 13th century. Its many sub regions, which were dominated by elites of small noblemen and freeholders, long time succeeded in…
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De stad en de dood
Het is een wijdverbreid idee dat (post-)middeleeuwse steden een sterfteoverschot hadden en zij slechts in leven konden blijven door de toestroom van migranten; een fenomeen dat bekend staat als het ‘urban graveyard’-effect. Over details valt te twisten, maar duidelijk is dat de stad en de dood dichter…
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Degradome analysis of vaccines
The objective is to develop in vitro antigen degradation assays in order to mimic the fate of the antigen in vivo.
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Praktische zaken - Toelating en aanmelding
Een medewerker van Frontoffice Studentenzaken legt uit waar je vooral rekening mee moet houden als je je wilt aanmelden bij de Universiteit Leiden.
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Music Cognition
Knowledge and culture subproject 1:
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Reports
Overview of the CML reports
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Next generation lipopeptide antibiotics
This thesis describes the evaluation of novel natural products with antibacterial activity enabled by total chemical synthesis.
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e-Coach: Tailored cognitive-behavioral e-Health care for patients with chronic somatic conditions
The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.
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Forum Antiquum Lecture Spring 2023: 'De mythen van Plato als denkinstrumenten'
Lecture
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Publications
Disclaimer: Manuscripts related to the Resilience Center are for academic purposes only and are not intended for mass distribution or copying. Please refer to applicable laws for fair use, including copyright holders' restrictions on publications.
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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Small molecule inhibitors of Nicotinamide N-Methyltransferase (NNMT)
NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…
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MicroGRICE: Greenhouse Gas Reduction in RICE: MICRO-biome climate smart applications
Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?
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Die Ersten Bauern Mitteleuropas
Eine Archäobotanische untersuchung zu Umwelt und Landwirtschaft der Ältesten Bankkeramik.
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Epistemological Inquiry into Islam’s Moral Economic Teachings, Legal Discourse, and Islamization Process
Mr. S. Al Daghistani defended his thesis on 30 November 2017
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Phenoconversion
Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…
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Parking garage Gorlaeus Building
, Wassenaarseweg 76, 2333 AL, Leiden
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Oudheid in de Hortus Botanicus
Welke planten in de Mediterrane tuin waren al bekend bij de oude Grieken en Romeinen, en hoe werden ze toegepast?
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Democratie, deugden, docentschap
On 8 November, Jordi Wiersma defended the thesis 'Democratie, deugden, docentschap: de docent als gids in de democratie'. The doctoral research was supervised by Andreas Kinneging and Paul van Geest.
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A three-step approach to supporting patient self-management in clinical practice
The aim of this project is to develop, evaluate, and multicentre implement a blended form of cardiac rehabilitation that uses a theory-based approach to guide patients to full self-management.
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Integrated life cycle assessment and life cycle costing of concrete recycling in the Netherlands
Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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Trends in social assistance, minimum income benefits and income polarization in an international perspective
Social assistance and minimum income benefits are important instruments as a safeguard against low income and poverty. There have been major developments in minimum income benefits both in developed and developing countries over the last decades. Our study collects several empirical studies regarding…
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The use of self- and peer assessment with video in courses on professional practice
How can video on professional practices in university courses be used in a valid and useful way for assessment and feedback?
- Italian 1
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Contact
Contact information & address
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Uitnoding Norbetinessenklooster Sint Catharinadal te Oosterhout
De drieëndertigste contactdag voor belangstellenden bij het Norbetinessenkloster Sint-Catharinadal vindt plaats op zaterdag 10 mei. Inschrijving voor 25 april.
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Biomolecular analyses of skeletal remains in the circum-Caribbean across the historical divide (A.D. 1000-1800)
As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.
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Low-Resource Chat-based Conversational Intelligence (LESSEN)
Access to information is a human right (United Nations, 1948). Information technology, such as search engines and recommender systems, has become the key mediator and facilitator to connect people to information (White, 2016). Conversational artificial intelligence (AI) technology is increasingly being…
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Handbook on life cycle assessment
Writing an operational guide to the ISO standards for LCA and related sub-projects.
- Italian 3
- Italian 4
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Tracking the Tocharians from Europe to China: a linguistic reconstruction
This project intends to provide an integrated linguistic assessment of the hypothesised migration route of the Tocharians.
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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Hoven in Holland, 900-1300
In welke mate hebben domaniale structuren de machtsvorming en nederzettingsontwikkeling in en van het gewest Holland bepaald?
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Cool little kids
Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands
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Fire and Human Origins
Correctly interpreting the patterns of fire evidence in the archaeological record will illuminate the origin of human fire use.
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Toward curriculum reform: an empirical research about the implementation of national mathematics curriculum reform in China
This is a research project on the implementation of national mathematics curriculum reform in Chinese junior high school. The research is expected to provide insight into the ways and reasons of mathematics teachers in Chinese junior high school for implementing national curriculum reform.
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Standardized and reproducible measurement of decision-making in mice
In science, it is of vital importance that multiple studies corroborate the same result. Researchers therefore need to know all the details of previous experiments in order to implement the procedures as exactly as possible. However, this is becoming a major problem in neuroscience, as animal studies…
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Probing the darkness: the link between baryons and dark matter
Promotor: Prof.dr. J. Schaye, Co-promotor: Marcello Cacciato
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The development and prevention of social anxiety in youth
What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?
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Towards a democratic school: experience and viewpoints of stakeholders in Vietnamese secondary schools
This dissertation aims to provide a critical view of Vietnamese secondary school stakeholders’ awareness of democratic education regarding the core educational democratic values and democratic acts within either the ‘physical’ or digital learning environment.
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The shadow side of positive organizational change: practitioners’ experience navigating dialectical tensions in appreciative inquiry
On 23 April, Sheila Haji defended the thesis 'The shadow side of positive organizational change: practitioners’ experience navigating dialectical tensions in appreciative inquiry'. The doctoral research was supervised by Jan Adriaanse, Mark Dechesne and Renee Heath.
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The influence of music training in speech processing
In this project, we plan to combine two strands of research in speech processing: (a) the impact of prosody on speech processing and (b) the impact of musical training on speech processing. In our project we will test 8 year-old children with different degrees of musical training: (a) primary school…
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Ready for Quantum?! (in Dutch)
Lecture, NGL-lezing
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Mapping and Fostering Teachers’ Sense of Agency in Inclusive Education
How can we map and foster Dutch secondary teachers’ agency in inclusive education practices?
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Contact
Contact Bio-organic Synthesis
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Contact
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