What is the effectiveness of two school-based skills-training programs in promoting mental health?

This book on Alba is edited by Maurits Ebben, Margriet Lacy-Bruijn and Rolof van Hövell tot Westerflier. Each of its fifteen chapters are dedicated to developing a new understanding of a sometimes misunderstood figure in European history.

The EU JudgeCo Platform provides valuable sources on cross-border insolvency court-to-court cooperation and communication in a EU context.

The Prison Project investigates to what extent imprisonment has consequences for the relapse, health, career and intimate relations of the (ex-)prisoners.

The Institute of Security and Global Affairs (ISGA) hosts two research journals and publishes the ISGA Reports series. Besides its own publications, researchers at ISGA also publish books or journal articles elsewhere. You can find all these external publications under Research output on the right.

Research in the History and International Studies 1900-present specialisation addresses the interconnectedness and interdependence of contemporary global political, economic and cultural developments from a multidisciplinary perspective which is rooted in the humanities.

People with a mild intellectual disability (MID) experience more loneliness than people without MID. In the COLLELO project, researchers from social and humanities disciplines collaborate with people with MID and their (in)formal networks to create an (online) learning community that aims to understand…

This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members study the design and functioning of Dutch political institutions as well as attitudes and behaviour of political elites and citizens.

To address major societal challenges, research needs to go beyond the boundaries of traditional disciplines. We believe this starts with education. By exposing students to people from different scientific fields, they learn to deal with diverse perspectives and can broaden their horizons. Professors…

Shell cooperates with theoretical physicists and chemists of Leiden University to research how quantum computer algorithms can help simulate complex molecules.

The Faculty of Archaeology's own home-grown journal Inter-Section has released a new volume. Inter-Section offers students and PhD candidates the unique chance to publish in a peer-reviewed journal. Karel Kuipers and Tullio Abruzzese contributed to the new volume.

Keep improving: that’s the philosophy of LEAN, a method to tackle practical problems at the workplace yourself. After a successful start in 2017, in 2019 a third group started working with the LEAN training in self-selected improvement trajectories. In October the participants received their diploma.…

Frans Preumayr's nineteenth century virtuosic bassoon repertoire - An approach with a fine Grenser & Wiesner bassoon from Dresden: Issues of material and technique. What techniques and tools must be developed by period bassoonists in order to successfully approach the performance of Frans Preumayr's…

Salma Balazadeh, Víctor Carrión, and Jos Raaijmakers, biologists at the Institute of Biology Leiden (IBL), have successfully applied for an NWO grant and got awarded 730.000 euros. The board of NWO Domain Applied and Engineering Sciences awarded funding for their project within the Open Technology Programme…

Point your talented students to Inter-Section! That is the main message of the journal’s Editorial Board. But what exactly is Inter-Section? ‘It is meant for students to create an opportunity to publish a peer-reviewed article during, or just after, their study.’

The Leiden Leadership Programme (LLP) employs experts in the field of leadership. They equip master's students from Leiden University, TU Delft and Erasmus University Rotterdam with the necessary leadership knowledge, insights and skills to increase their social impact.

In this inspiration lab, Prof. Sandra Groeneveld and Matthijs de Jong (Deloitte) will share their vision on the Future of Work. What are the trends and developments in the fields of Organisation Theory and Human Resource Management? What is the impact on unemployment rates? And what is the impact on…

Uniting an international consortium of scholars, the Skandapurāṇa Project comprises a team of researchers working in fields across the Humanities. We are creating a critical edition of a foundational work of purāṇic literature and, in doing so, tracing the dynamics of a textual tradition to better understand…

The second day of our online Well Being week is about productivity. We called it Work It Wednesday.

What are the immediate and lasting effects of the colonial encounters on indigenous Caribbean cultures and societies and what were the intercultural dynamics that took place during the colonisation processes? How can the study of indigenous Caribbean histories contribute to a more sophisticated awareness…

In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model

If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.

Smartphone behaviors are so common but how does the brain generate this behavior? The Cognition in the digital environment laboratory (CODELAB) investigated the brain activity surrounding smartphone interactions with the help of Artificial Intelligence. According to their research, the brain fluidly…

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…

In Microbial Sciences, we perform multidisciplinary research to understand the structure and function of microbes at all levels of biological organization, from small molecules and cellular structures at atomic resolution to multicellular communities.

A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…

Developing computational algorithms for structural biology -A high resolution, three dimensional view of a molecule provides detailed information that help elucidate its function: by knowing the exact arrangement of atoms in a molecule, we can understand disease, develop drugs to combat them and improve…

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

Dementia is a progressive disease, diagnosed at a relatively late stage when intervention may not be effective. Aim of the research is to study scans of brain networks to help discover the early network changes related to dementia. Early diagnosis may benefit effectiveness of future treatment.

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Source: Eur J Med Chem (2015)

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.

Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen

Proteases degrade matrix molecules in the atherosclerotic plaque, thereby reducing atherosclerotic plaque stability. Mast cells, that contain proteases such as tryptase and chymase, have been identified at the site of rupture in specimens of human coronary arteries and their number in the plaque was…

This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.