Can we link multiple components from herbal extracts with their biological activities?

How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…

Bioarchaeology covers the study of all biological remains from archaeological sites.

Promotor: J. A. Bouwstra

Timely, adequate and optimal treatment of infectious diseases is essential for the survival of patients with bacterial infections (Surviving Sepsis campaign).

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon

The BENEFIT programme is a public-private ecosystem in a national consortium, aiming to support patients with cardiovascular diseases in their own home setting for a long-term healthy lifestyle.

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.

Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…

LUC graduates have an internationally-recognised Bachelors honours degree (BA/BSc) that qualifies them to apply for competitive programmes at top research universities. Over 90% of our alumni continue their studies into a master programme.

Biotherapeutics or biologics, such as proteins, peptides, and nucleic acids, comprise an increasing share of the pharmaceutical market, whilst offering new therapies for difficult-to-treat diseases. Most notable is their contribution to the vaccination efforts during the COVID-19 pandemic. In most cases,…

The research at The Metabolomics & Analytics Centre is centered around developing innovating analytical methods to enable metabolomics-driven systems biology in personalized health strategies.

If you wish to know exactly what is going on in a healthy or sick human body, and at various levels such as molecule, cell, tissue, organ, larger systems and a person as a whole? Do you wish to learn how to do research which contributes to diagnoses, treatment and prevention of diseases? Then the bachelor…

In the master's programme Biomedical Sciences you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…

In the master's programme Biomedical Sciences you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…

Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Natashe Lemos Dekker addresses the experiences of family members of people with dementia as they expressed their sense of gradually losing the person with dementia in the article 'Anticipatory Grief in Dementia: An Ethnographic Study of Loss and Connection' published in Culture, Medicine, and Psychi…

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

A Pointer investigation has found that more than 30 Dutch podcasts regularly spread misinformation. Assistant professor Michael Klos spoke to Pointer about preventing misinformation in the media: ‘Realistically, you’re never going to achieve 100% moderation.’

On this page you can learn more about the history of our Faculty Awards and view the previous winners.

Tracking early human behaviour through plant processing and -exploitation.

The Journal of Global Slavery (JGS) aims to advance and promote a greater understanding of slavery and post-slavery from comparative, transregional, and/or global perspectives. It especially underscores the global and globalizing nature of slavery in world history.

An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.

Diplomatica: A Journal of Diplomacy and Society addresses the broad range of work being done across the social sciences and the humanities that takes diplomacy as its focus of investigation.

The people behind The Hague Journal of Diplomacy and its online platform.

Leids onderzoek naar bestraffing komt tot stand uit verschillende disciplines. Het onderzoeksproject kent een juridische, criminologische, sociaalwetenschappelijke en filosofische invalshoek.

IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.

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PhD defence

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Working as a diplomat for the Ministry of Foreign Affairs: for many students it would be their dream. Alumnus Tom Groot Haar is busy making it a reality. 'My career seems like a preconceived plan, but it wasn't.'

How can saxophone without mouthpiece techniques be accurately and consistently comprehended and explained?

The main objective of this research is to map out the cities of the Roman Near East in the imperial period, with a focus on location, city size and urban features, in order to study the form the urban system and its levels of integration.

This project investigates the transposition of natural historical material, knowledge and vision, between different media (collection, scientific drawing, academic texts, the visual arts and/or literature) – a transmission that happens in the borderline between the traditional, emblematic worldview…

Self-censorship violates principles of a free society but few people want to take the role of the martyr.

Artistic research has come of age, and with it the Orpheus Institute. Founded twenty years ago, the Institute’s purpose from the start has been to pursue research through the practice of musicians.

In October 2014 a new publication on artistic research has been launched. The book is called Artistic Experimentation in Music. An Anthology, edited by Darla Crispin and Bob Gilmore, and published by Leuven University Press.

Plant Sciences' contribution to the Host-Microbe Interactions research theme is to dissect how microorganisms and microbiomes interact with the plant host and the insects on those plants, and how these insights may be harnessed to improve plant growth and health, by steering microbiome composition and…

Global climate change is manifest by local-scale changes in precipitation and temperature patterns, including the frequency of extreme weather events (EWEs). EWEs are associated with a myriad range of adverse environmental and societal consequences, including negative impacts to agriculture and food…

Negotiation can only really be an alternative to warfare, if the parties agree on a framework of rules and procedures. And if the confidence of the partners may increase in another. But negotiations continue to wage war by peaceful means.

Early Modern Medievalisms: The Interplay between Scholarly Reflection and Artistic Production

The Nietzsche-Wörterbuch (NWB) has evolved into a long-term, multi-volume work on a global scale with around 30 contributors from a range of disciplines located all over the world

Managing scarcity to serve the public interest is a classic government task. An important way to execute this task is by allocating individual rights that are only available in limited quantities, such as CO2 emission allowances, gambling licences, subsidies, radio frequencies, public contracts and…

This subproject of 'From Homo Economicus to Political Animal' will be on ancient analogues for modern-day “ersatz economics”, the economics of the “man in the street”.