Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…

From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

Exploring the landscapes of mental health and cardiometabolic research.

Five talks will be given during the Leiden Science Family Day: two children's lectures and three lectures for adults. Will you be there ?

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Supervisor: Anna Vlachodimou

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Lecture

The ‘Contagious!’ exhibition was set to open at Rijksmuseum Boerhaave in April but had to be postponed because of the corona crisis. The museum hasn’t been twiddling its thumbs in the meantime. The exhibition will now open on 16 July, and the corona crisis has a major role.

How De Haan is using language in general and his specific style of language in particular to provide truth, solidarity and justice for both the individual and the collective?

How do societies move forward with sustainable, effective and efficient management of Earth's water resources?

The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…

A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.

PhD defence

An inclusive society in which everyone has equal access to health and wealth is the focus of the new Leiden-Delft-Erasmus Centre on the Governance of Migration and Diversity. Professor of Migration History, Marlou Schrover, also works at the new centre. ‘It is important to add a historical perspective…

Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

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This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

Assistant Professor at the Metabolomics group, LUMC, The Nederlands

Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.

The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.

Promotor: Prof.dr. J.P. Abrahams

The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…

The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.

Those who look ahead can see we build the future together.

During the 7th annual meeting of the Association for Researchers in Psychology and Health (ARPH) Sylvia van Beugen, from the Health, Medical and Neuropsychology unit, was awarded with the ’Best PhD Thesis Award’ for her dissertation ‘Psychodermatology 2.0: Towards improved assessment and effective digital…

The overall aim of the project is to investigate interests and their development over time in a daily life context, with particular attention for the transition from late secondary to post secondary education, and from late post secondary education to early career.

Environmental scientist Rutger Hoekstra addressed the General Assembly of the United Nations on 12 April. And that’s quite a big thing to do. How do you get there as a scientist? And, more importantly, what was his message? In eight questions, Rutger explains what he does and why.

Find out who to contact with press enquiries and how we tell the world our news.

PhD defence

Sound & Score brings together music expertise from prominent international researchers and performers exploring the intimate relations between sound, score and notation, and the artistic possibilities that this relationship yields for performers, composers and listeners.

Associates of Leiden University Center for Intercultural Philosophy

This book looks to existential thinkers for reasons to hope immortal life could be worth living. It injects new arguments and insights into the debate about the desirability of immortality, and tackles related issues such as boredom, personal identity, technological progress, and the meaning of life…

Slavoj Žižek is one of the most prominent public intellectuals of the left. His central claim holds that “today, it is more crucial than ever to continue to question the very foundations of capitalism as a global system”.

This book focuses on policing in city-regions in Europe bringing together experts from across the continent to develop a sociology of urban policing and a unique methodology for comparing different metropolises in the same country.

International trade plays a critical role in global food security, with global consumption having highly localized environmental impacts.

We are a dynamic research group at the Leiden Institute of Physics. Our aim is to explore and understand quantum materials, including strange metals, high-temperature superconductors, and quantum critical electron matter.

The emissions of the Chinese industrial sector alone comprise 24.1% of global emissions (7.8 GtCyr−1 in 2015). This makes Chinese industrial emissions of unique national and international relevance in climate policy. This study reports a literature survey that quantitatively describes the evolution…

Politics, Culture and National Identities investigates a wide range of national political cultures in Europe and the Americas in the 19th and 20th centuries.