495 search results for “aalten jong 1988 1988 emma a novel” in the Public website
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Former LAPP Students
The following students have been part of LAPP:
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Novel detection method for iron in Alzheimer’s brain
For many years, scientists have observed a correlation between Alzheimer’s disease and a surplus of iron in the brain. However, a causal link between the two has not been proven yet. We lack knowledge concerning the specific form of iron that is involved in the development of neurodegenerative diseases.…
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In touch with the dead
A study of early medieval reopened graves
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Optimality
Optimality in plant properties and processing.
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Crisis and change in European Union foreign policy
How do crises produce changes in specific European Union foreign policy areas, and how should we conceptualise these policy changes?
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Between life and death: organizational change in central state bureaucracies in cross-national comparison
Identifying and explaining change in the structure of central state bureaucracies and the determinants of survival of individual public organizations are two closely related areas of research in public administration. We aim to bridge the gap between these two main strands of studies of organizational…
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Replacing fear with something new: Using novelty to unlearn fear.
This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.
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Bio-inspired Computing
We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.
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Film and Literary Studies (BA)
Do you enjoy a great story? In the Bachelor's programme Film and Literary Studies at Leiden University you study the stories behind the stories. Because what makes a novel fascinating or a horror movie frightening? Study film, literature and media from around the entire world and discover the differences…
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Single-electrolyte isotachophoresis: on-chip analyte focusing and separation
Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto
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AI application in pathology reveals novel insights in endometrial cancer diagnostics
Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…
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Anticancer compounds from actinomycetes
How can we find novel natural products from Actinomycetes that act as growth modulators on mammalian cells? Can we harvest and develop the potential of these novel compounds for industrial and medical biotechnology?
- History of Diplomacy
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TRAFIG: Transnational Figurations of Displacement: Connectivity and mobility as solutions to protracted refugee situations
How can we promote more durable solutions to protracted refugee situations and which roles can connectivity and mobility of displaced people play to improve protection and resilience?
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The Implications of ISIS (the “Islamic State”) for Islamic Movements and the Middle East
Political Islam is not new to the Middle East, but the appearance of ISIS has stretched the phenomenon to the extreme.
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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Glucocerebrosidase and glycolipids: In and beyond the lysosome
The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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Knots in plasma
A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.
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Resisters and protesters
One of the stained glass windows in the Great Auditorium of the Academy Building is dedicated to the students and staff of Leiden University who resisted, protested against, or became victims of the German occupiers. It depicts female figures alongside male ones.
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‘Do Not Say They Are Dead’: The Political Use of Mystical and Religious Concepts in the Persian Poetry of the Iran-Iraq War (1980-88)
The chief aim of this study is to explore how classical Persian poetry and the Persian mysticism that is interwoven with the poetry have been used in the new politics of the Islamic Republic of Iran, especially during the Iran-Iraq war.
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Reedijk Symposium 2024: Understanding and exploiting epi-glycome active enzymes
Lecture
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Turtles all the way down: multiscale simulations connecting star and planet formation
The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.
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Rethinking Political Obligation. Moral Principles, Communal Ties, Citizenship
Why obey the state? Dorota Mokrosińska presents a fresh analysis of the most influential theories of political obligation and develops a novel approach to this foundational problem of political philosophy, an intriguing combination of the elements of natural duty and associative theories.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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Egypt beyond representation
This research develops and applies a new approach to study Aegyptiaca Romana from a bottom-up, Roman perspective.
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An analytical framework for postmortems of European foreign policy: should decision-makers have been surprised?
This paper develops a novel theoretical framework for the conduct of postmortems after major foreign policy surprises for the European Union and its member states.
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Moved by the tears of others: emotion networking in the heritage sphere
There is no heritage without emotional sharing and clashing. This article explores the involvement of divergent emotions in heritage making by discussing the debate series of Imagine IC and the Reinwardt Academy and zooming in on the commemoration of slavery and imagery of ‘Black Pete’ in the Netherlands.…
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Managing R&D in Science-Based Economies
Corporate R&D organizations and their relation to academic laboratories.
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Style in Dutch literary prose
Terms used by literary critics in characterizing the style of novels are often impressionistic (‘baroque’, ‘austere’, ‘vivid’, ‘cerebral’ etc.). Foundations for such evaluations are usually not provided. A scientific way of studying and explaining style is lacking in present day Dutch Studies. Suzanne…
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Martyrs are sometimes women
Women behind the front play an important role in a large proportion of Iranian novels, written on the Iran and Iraq-war (1980-1988). But their martyrdom is an uncommon theme. Saeedeh Shahnahpur will give a lecture on this subject on 16 February.
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: J.P. Abrahams, Co-Promotor: N.S. Pannu
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Psychosomatic Imagery. Photographic Reflections on Mental Disorders
Introduces a novel trope of photographic images dealing with states of mental disorders; focuses on photographs that visualize disturbed corporeal and mental perceptions of the world and connects medium-specific characteristics of photography to concepts from mental disorder studies.
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Kv 11.1 (hERG)-induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv 11.1 (hERG) inhibitors
Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)
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Prof. Tim Koopmans
Tim Koopmans is one of the great minds in the history of Dutch and European legal scholarship. He taught law as a professor in Leiden and other universities, among which Ghent, Cambridge, Utrecht. He practiced it as a judge in the European Court of Justice and Advocate-General in the Dutch Supreme Court,…
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MARBLES - Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases
To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.
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The NKG2A / HLA-E axis a novel target for immune checkpoint therapy
PhD defence
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Stereotype
The role of grave sets in Corded Ware and Bell Beaker funerary practices
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Dr. Theo Reijmers
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The Texture of the Lexicon
In this volume, Ray Jackendoff and Jenny Audring embark on a major reconceptualization of linguistic theory as seen through the lens of morphology. Their approach, Relational Morphology, extends the Parallel Architecture developed by Jackendoff in Foundations of Language (2002), Simpler Syntax (2005),…
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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Institutional sources of legitimacy in multistakeholder global governance at ICANN
This article investigates the sources of legitimacy in multistakeholderism as a major alternative approach to intergovernmental global governance.
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Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.