PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

New technology offers many new possibilities for research, such as on dementia. ‘Organ-on-a-chip’ is a new technology in which small bits of organ are grown out of stem cells on a small plastic plate. A small piece of blood vessel, heart or nerve offers many new possibilities for research, such as…

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

Professor of Ecotoxicology Martina Vijver and lecturer Maarten Schrama are the founders and managers of the Living Lab. As well as these two researchers, a number of other ecologists and biologists are involved in the research at the Lab.

The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.

Parasitic worms and stomach bacteria suppress immune reactions such as allergic responses. Parasitologist Hermelijn Smits and lung specialist Christian Taube from the LUMC are trying to learn from these micro-organisms.

Cognitive decline (amongst other problems with attention, concentration, memory) is a common symptom in patients with a variety of brain disorders and has been related to healthy ageing as well. People suffering from cognitive deficits are often significantly hampered in their day-to-day functioning…

The Basics and Applications to Plant Sciences will be held physical. See below for more information.

With the emergence of new methods and technologies such as improved DNA analysis and big data, archaeological research has changed radically in recent decades. The researchers from the Department of Archaeological Sciences at the Faculty of Archaeology use new scientific knowledge to answer fundamental…

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

Courses cover a broad range of relevant subjects and provide in-depth theoretical knowledge as well as training in practical skills and advanced research tools.

The Faculty of Science

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

The importance of a healthy lifestyle does not receive the attention it deserves, as the coronavirus pandemic made painfully clear. Twelve behavioural scientists, including Professor Behavioral Interventions in Population Health Management Marieke Adriaanse and Professor of Health Psychology Andrea…

Professor of Radiology Lioe-Fee de Geus-Oei was already a professor at LUMC and the University of Twente. As Medical Delta professor, she has now also been appointed at Delft University of Technology. 'Talking with people from other disciplines always makes me immensely humble, because they look at…

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Some species of proteins which can form liquid-like condensates, also exhibit growth into fibers (or fibrils). One particularly interesting set of such proteins are those that are associated with neurodegeneration in which the fiber growth may be related to the pathological fibrils observed in disea…

The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

The indane (2,3-dihydro-1H-indene) ring system is an attractive scaffold for biologically active compounds due to the combination of aromatic and aliphatic properties fused together in one rigid system.

Promotores: A.H. Meijer, H.P. Spaink

From as early as classical antiquity there has been an interplay between literature and medicine.

On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…

The Laboratory for Human Osteoarchaeology specialises in the macroscopic and microscopic analysis of human remains. We use cutting edge scientific approaches to address archaeological, historical, and anthropological research questions. In addition to paleopathological, histological, and 3D scanning…

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Supervisor: P.J.J. Hooykaas

List of Support Departments at LION and the Faculty of Science

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

On this page, you can find video's explaining the research of LUCAS members.

The aim of this project is to develop accurate but interpretable ensemble learning methods for high-dimensional multi-domain data.

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.

Promotor: W. Jiskoot, Co-promotor: A. Hawe

This project explores themes at the intersection of maritime history and environmental history by looking at the problems Dutch ships encountered in the different climates of the Atlantic and Indian Ocean worlds, and the solutions they could provide.

Can the pink-pigmented microbe Methylobacterium extorquens be genetically engineered to convert the sustainable raw material methanol into antibiotics?