1,863 search results for “R programming” in the Public website
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Mechanisms and consequences of horizontal gene transfer in cell wall-deficient cells of Kitasatospora viridifaciens
The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity
The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.
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Resolving rapid radiations
What are the phylogenetic relationships among the members of speciation bursts?
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The Teaching of Khety and Its Use as an Educational Tool in Ancient Egypt
On Wednesday 23 October 2024 Judith Jurjens successfully defended a doctoral thesis and graduated.
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Protein-polyelectrolyte interactions: Monitoring particle formation and growth by nanoparticle tracking analysis and flow imaging microscopy
The purpose of this study was to investigate the formation and growth kinetics of complexes between proteins and oppositely charged polyelectrolytes.
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The Sociolinguistics of Rhotacization in the Beijing Speech Community
On 21 September 2022 H. Hu successfully defended a doctoral thesis and graduated.
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Control processes in children’s word productions
How does task context affect children’s word productions?
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Industry science links
How to facilitate the translation of science into innovation
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Photothermal circular dichroism studies of single nanoparticles
In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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The Infrared Spectrum of Massive Protostars
We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.
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The Agro Pontino archaeological survey
ASLU 11
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Fisheries in the Waza Logone Floodplain. An Analysis of the Status of the Fisheries Sector and Mitigation of Conflicts within the Sector in North
Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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The advent of Abrī: the first wave of paper marbling in the long 16th century (ca. 1496-1616CE)
On Thursday 21 November 2024 Jake Benson successfully defended a doctoral thesis and graduated.
- Meet our staff
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Biology and Business Studies (MSc)
The master’s specialisation Biology and Business Studies at Leiden University bridges science and business development by focusing on areas such as technology management, innovation, entrepeneurship, operations, and decision making.
- Meet our staff
- Leiden University
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Education Office
The Education Office supervises and supports all teaching and student affairs
- Science (Wis- en Natuurwetenschappen)
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Student associations
Leiden is bursting with student associations, from sports to music associations and from social to cultural associations. And this is good news because they will help you make more than just friends.
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Student associations
If you are new to Leiden, it might be a good idea to join one of its many student associations. You’ll quickly get to know people and build up a network that will continue to prove its worth long after you’ve graduated from your master’s.
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Joan van der Waals colloquium
The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.
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voices: Economy as a Matter of Fact and a Matter of Concern by Douglas R. Holmes (Binghamton University)
Lecture, Research Seminar
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Environmental and genetic drivers of wood and lignin formation in flowering plants
In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.
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Economies of Destruction
The emergence of metalwork deposition during the Bronze Age in Northwest Europe, c. 2300-1500 BC
- Paradiplomacy
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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The pottery workshops in Fustat
Dr Kim Duistermaat (NVIC) en Niels Groot (TU Delft)
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
- Health Diplomacy
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Wetenschap erkent potentieel van rechtspraak in wijken
Theoretische onderbouwing laat zien dat wijkrechtspraak effectief kan zijn. Dat blijkt uit een vandaag gepresenteerde studie in opdracht van het WODC. Rechters kunnen vanuit een zitting in een wijkcentrum vaak beter ingrijpen dan vanuit de rechtszaal en met meer vertrouwen.
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Research
Labour law is constantly changing. Concurrently, the laws dealing with workers address fundamental issues which are invariably of major significance and value. The research carried out at the Department of Labour Law and Social Security focusses on both the (constant) changes in labour law and social…
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Publications and output
Here you'll find selected publications and media attention from our group.
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Education
Our educational programmes span the entire spectrum of pharmaceutical education, from training of the next generation drug researchers in the areas of drug design, drug action, and drug use to educating the pharmacists of the future.
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Global Brexit: the international ramifications of the UK’s withdrawal from the EU
Ending the United Kingdom’s (UK) forty-seven year European Union (EU) membership has fundamentally transformed its relationship with the EU. After years of tumultuous negotiations, international law now once again governs the UK’s relationship with the EU. This has resulted in a sophisticated body of…
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Our facilities
In support of the research and education, the Leiden Institute of Advanced Computer Science (LIACS) has a Research and Education laboratory at its disposal. Within this environment, we can offer machines that go beyond normal office automisation and production.
- El-Hosh
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A PCAD-model for fish to study the impact of airgun sound exposure on free-ranging cod
We are developing the conceptual framework, which is new to this taxonomic group, and evaluate the current state of the art with respect to all critical parameters and transfer functions for a fully developed Population Consequences of Acoustic Disturbance (PCAD) model.
- Jan van Ruitenbeek Lab - Atomic and Molecular Conductors
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Topic: Stigmatization in patients with chronic health conditions
Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…
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Cleveringa chair
The Cleveringa chair was installed by Leiden University in memory of Professor Rudolph Pabus Cleveringa and the courage he demonstrated in November 1940 during the German occupation . It also commemorates the liberation of the Netherlands in 1945.
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Memory boost: A novelty-exposure intervention to counteract memory decline.
This project aims to identify which aspects of exploring a novel environment produce beneficial effects on memory. The effects of novelty will be investigated across the lifespan, including children, adolescents and older adults.
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Good employment practices in relation to employee well-being
Both good employer practices and good employee practices are open norms. These open norms can lead to uncertainty about what employers should focus on and what rights (and obligations) employees have in that respect. The objective of this study is to give substance to the norm of good employment practices…