Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…

Steven Frost defended his thesis on 6 June 2017

Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

PhD defence

Promoter: J.G.E.M.Fraaije, Co-promotor: A. Kros

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Promotores: B.R. Katzy, J. de Vries, Co-Promotor: L.P. Groenewegen

PhD defence

Christopher Green defended his thesis on 26 February 2020

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Promotor: G.R. de Snoo

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Leiden Journal of Pottery Studies 22, 2006

Bas Verberk defended his thesis on 6 September 2016

In the article Multimodality: Reshaping Anthropology, Mark Westmoreland describes how multimodality provides anthropologists with a new perspective on how we conduct research, produce scholarship, teach students, and interact with diverse audiences.

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

In Women and Property Rights in Indonesian Islamic Contexts, eight scholars of Indonesian Islam examine women’s access to property in law courts and in village settings.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

Oxidation is a common degradation pathway that affects therapeutic proteins and peptides during production, purification, formulation, transportation, storage and handling of solid and liquid preparations. In the present work we review the scientific literature about structural and biological consequences…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.

From as early as classical antiquity there has been an interplay between literature and medicine.

On 18 May 2022 Lan-Yi Yang successfully defended a doctoral thesis and graduated.

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

A study on the utilisation of Iron Age rectangular structures and related depositional practices in the Low Countries

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Musters

On 24 October 2023 Jurre Knoest successfully defended a doctoral thesis and graduated.

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

On 12 April 2022 Alok Oak successfully defended a doctoral thesis and graduated.

, Maliebaan 30, 2311 CC, Leiden

Overkleeft

Promotor: Prof.dr. J. Brouwer, Co-promotor: Dr. Remus Th. Dame

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

The dissociative chemisorption of methane on metal surfaces is of fundamental and practical interest, being a rate-limiting step in the steam reforming process. The reaction is best modeled with quantum dynamics calculations, but these are currently not guaranteed to produce accurate results because…

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

Over time Dutch and Indonesian composers, performers and music scholars have inspired each other and they continue to do so. The presence of the Dutch in the Netherlands East-Indies and Indonesia, but also the existence of large diasporic communities in the Netherlands have contributed to a mutual exchange…

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.