We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

Dr. Barbara Veselka recently published an article on Vitamin D deficiency in 19th century skeletal remains in the International Journal of Paleopathology.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…

What does it mean to eat healthily and responsibly? This question is gaining a new urgency now that in many countries undernourishment is being overtaken by diseases of affluence, such as obesity, and we are also becoming more aware of the environmental impact of our eating habits. It’s time to take…

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

Supervisor: Lizi Xia

What is the role of auxin in the initiation and process of somatic embryogenesis?

On the occasion of the Women & Girls in Science Day, BBC Science Focus Magazine highlighted 6 prominent female chemists. Among them is Leiden professor Ewine van Dishoeck: 'Astrochemist investigating the building blocks of life'.

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

On 18 May 2022 Lan-Yi Yang successfully defended a doctoral thesis and graduated.

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

Heart failure is a major health care problem with high mortality.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

JUSTREMIT is an ERC-funded project that brings together political theory, ethnography, and security studies in an interdisciplinary study of remittances and global justice.

Together with patient representatives, clinician-researchers from Radboucumc (Internal Medicine) Amsterdam UMC and researchers from Leiden University (Andrea Evers and Henriët van Middendorp) have received the Medical Inspirator Prize 2019 of The Netherlands Organisation for Health Research and Development…

What is the role of cell wall-deficiency in the persistence of tuberculosis?

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Cities, Migration and Global Interdependence focuses on inequality in all its forms. You will approach this subject from an intersectional perspective. Since categories of power and identity are always intertwined, the courses in the programme reflect this reality. This means you will study how societies…

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Which plant leaf characteristics are involved in thrips resistance in tomato?

Why did 'character', 'habit', and 'virtue' serve as key terms in late 19th and early 20th-century scholarly correspondences, biographies, and obituaries? Why did scholars around 1900 display so much interest in the working habits and character traits of what they called the 'scholarly self'?

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Promotor: S.M. Verduyn Lunel

A multi-disciplinary approach to past lifestyles and cultural practices

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

How do mycobacteria subvert the defenses of host immune cells?

Excavations at Geleen-Janskamerveld 1990/1991

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

This edited volume by Jeff Fynn-Paul pushes forward the debate on the role of entrepreneurs in making war and building states in Europe and the Ottoman Empire.

On 1 October 2019 the Hazelhoff Centre for Financial law hosted its 19th guest lecture starring Paul Sharma, managing director at Alvarez & Marsal and co-head of the European Financial Industry Regulatory Advisory Services practices.

The number of women in the Netherlands dying before, during or after childbirth has halved.

Can drug screening for tuberculosis treatment be made more efficient?