Wim Klooster and Gert Oostindie present a fresh look at the Dutch Atlantic in the period following the imperial moment of the seventeenth century. This epoch (1680–1815), the authors argue, marked a distinct and significant era in which Dutch military power declined and Dutch colonies began to chart…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

In recent years, the issue of mass tort litigation and the fair and efficient settlement and adjudication of mass torts has drawn increasing attention in academic discourse, legal practice and policy debates.

How did parties as political organizations emerge?

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Dr. Theo Reijmers

Ramautar

Promotor: Prof.dr. T. Hankemeier, Co-promotor: T.H. Reijmers

It is a tragic fact that mass atrocities have been, and are being, committed across the world. The international community, while condemning these acts, often stands idly by. This conundrum raises a host of empirical, legal, and normative questions regarding the role of public opinion in responding…

My work focuses on a class of astronomical objects called protoplanetary disks.

On the 9th of June Bahaddin Budak successfully defended a doctoral thesis and graduated.

Promotor: Prof.dr. E.F. van Dishoeck, Co-promotor: S. Bruderer

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: Dr. H.Hoekstra

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.

Leiden University has participated in an international study carried out by the CARMENES consortium, which has discovered two small, terrestrial planets around Teegarden’s Star. The planets have masses similar to Earth and their temperatures could be mild enough to sustain liquid water on their surf…

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

PhD defence

This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.

Leiden astronomer Anthony Brown is part of Nature’s 10: the ten people who mattered in science in 2018, according to the leading science journal. Working behind the scenes, Brown is the astronomer who coordinated the release of Gaia’s long-awaited bounty of Milky Way data.

Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

Leiden astronomer Anthony Brown had the honour to give the prestigious Spitzer Lectures at Princeton University. In five lectures spread over the beginning of May, he gave an insight into the Gaia Mission. ‘One of the intellectual highlights of the year.’

Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…

Development of micro-scale analytical tools to be used to address relevant biomedical questions in the field of neuroscience, and other application areas intrinsically dealing with small sample amounts.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

In the field of metabolomics, capillary electrophoresis-mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In order to highlight the unique features of CE-MS for metabolomics studies, Dr. Rawi Ramautar…

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

In the group presentation in the CSM-elective ‘governance of crime and social disorder’ of teacher Elke Devroe students battled again for the winning lot, namely this blog published in the Leiden university Website.

Promotor: Prof.dr. S.F. Portegies Zwart

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

A staggering 6.5 billion chicks are killed worldwide every year. These are generally male chicks that are of no economic value. In Ovo has developed technology that can quickly determine the sex of a chick, to ensure that only female chicks are hatched. The first 150,000 chicks have now hatched in this…

PhD at Leiden University and Bruker - the Netherlands

The Dutch biotech start-up In Ovo is the first company to develop a large-scale solution for determining the sex of a chick while it is still in the egg. This fast and cheap technique can be applied mechanically at hatcheries, which was not possible before.

Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…

A Dutch-led team of astronomers has discovered that high-mass stars are formed differently from their smaller siblings. Whereas small stars are often surrounded by an orderly disk of dust and matter, the supply of matter to large stars is a chaotic mess. The researchers used the Atacama Large Millimeter/submillimeter…