Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

The aim of this thesis was to study the link between hearing loss, language skills, and social functioning in deaf and hard of hearing (DHH) children. Sufficient language skills are an essential prerequisite to develop appropriate communication skills, in order to join in conversations with others.…

During the course of drug discovery translational steps are made.

The recently published book ‘Avian Cognition’ is the first multi-author book to provide a comprehensive treatment of the cognitive abilities of birds and how they compare to those of other animals. Carel ten Cate, professor of animal behavior at the Institute of Biology, and Susan D. Healy (StAndrews…

The project ‘Between the Holy Land and the World’ proposes a connected history of the Christian communities in the Near East (1900-1948) by means of a study of unpublished Franciscan and Dominican photographic collections.

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

PhD defence

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

Morality, mathematics, geometry, geography, music, navigation, and language are traditionally viewed as uniquely human cultural achievements and abilities. The study of their development and variation is classified as part of the humanities and social sciences. These fields have been mainly studied…

Fred Janssen is curious about how best to teach students and students to gain a good understanding of complex ‘swamp situations’. This is the subject of his inaugural lecture as Professor of Science Education at the ICLON and the Faculty of Science. Inaugural address 19 June 2017.

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

What are the precise identities, possibilities and current practice examples of the various time frames in music and what bearings do they have individually and in combinations on the speed of the music?

Promotor: E.F. Smets Co-promotor: J. Geml

How is social cognition shaped by our knowledge of language and stories?

This research will focus on the relationship between the musical structure and musical time in the performance of 19th century music.

Birds sing to be heard, but how do they cope with increasing noise levels? Which species persist in cities and why? And do they thrive or suffer in the urban soundscape?

Fatemeh (Simin) Tabassi Mofrad has recently received a project grant (€ 25,000) from LUF/Gratama Foundation for her ideas in investigating sex-by-genotype interactions in brain functions. She has a multidisciplinary research perspective which enables her to look at research issues from different angles.…

On 4 and 5 November 2021 an ICOG-workshop will be held on the cognitive turn in history. It is possible to attend this workshop online. The participants of the workshop are cultural and intellectual historians of the pre-modern periods and/or of the historiography of academia from a long-term perspective,…

In September 2019, Manon Mulckhuyse will start a position as assistant professor in the Cognitive Psychology Unit.

Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963

To what end and how does Plautus constantly underline the Helleni(sti)c provenance of his art? How does this aspect relate the author’s originality?

Are disturbances to the brain, such as Alzheimer's or autism, linked to specific defects in the underlying communication networks in the brain? If this is the case, subtle changes in the networks can act as a marker for brain disturbances. Neuroscientist Serge Rombouts will be investigating this, together…