This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

The chemical synthesis of inhibitors and probes targeting endo-glycosidases.

Promotores: F.H.J. Redig, W.T.F. den Hollander

This project investigates the globalization and cultural mediation of palliative care practices, policies and discourses.

In specialist organ literature a negative verdict is given on organs and organ specialists from the 1930’s. Did the same verdict apply to Johan van Meurs’ (1903-1986) work? Which role does Van Meurs’ collection of organ specifications play in the historical research on the organ?

An international team of researchers observed the full extent of the evolution of hot gas produced by an active black hole for the first time. As it evolves, the hot gas encompasses a much larger area than previously thought and even impacts objects residing at great distances. Their study is published…

We talk too little about silence, thinks university lecturer Gerlov van Engelenhoven. He has been awarded a Veni grant to investigate the role of silence in protest movements. Does silence sometimes really say more than a thousand words?

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

The Centre for the Study of Political Parties and Representation (CSPPR) aims to serve as an interdisciplinary platform for scholars of Leiden University for research focusing on the historical and contemporary operation and functioning of political parties and political representation, with a particular…

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

On the 12th of November, Xander Vertegaal successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Xander on this achievement!

Combined hormonal contraceptives (CHC) are associated with an increased risk of venous thromboembolism (VTE). In 2013, a review was published by the European Medicines Agency (EMA). In this review, the authors concluded that the risk of VTE varies by the type of progesterone in the CHC. Subsequently,…

What is the cost of visual complexity? This dissertation sets out to determine the effect of the complexity of word formation on the legibility of Arabic and the role that vocalization plays in reading.

On 14 December 2022, students of the course Social and Ecological Activism in the Visual Arts (as part of the Creative Strategies for a Society in Change minor) presented and performed their final collective project at BAK, basis voor actuele kunst, Utrecht: the Water Cultures Institute group role-playing…

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Young Dutch people’s reading skills have been declining for years. The main reason for this is that many have difficulty with reading at greater depth. Teach pupils to read actively in order to construct meaning is what Leiden researchers Paul van den Broek, Christine Espin and Anne Helder write in…

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

The gripping story of a collective passion for freedom that shook the world.

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

On the 12th of December, Eleanor Dutton successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Eleanor on this achievement.

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

This thesis attempts to establish a dialogue between the modern and the medieval traditions in logic, by means of ‘translations’ of the medieval logical theories into the modern framework of symbolic logic, i.e. formalizations.

Nico Staring, researcher in Egyptian art, culture and history, is taking part in the Leiden-Turin excavations in Saqqara, Egypt. The site of Saqqara is interesting because it was utilized as a cemetery but also the veneration of gods for a period of more than 3000 years, between ca. 3000 BCE to the…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Can we predict fluctuations in suicidal ideation in a person’s daily life, from hour to hour?

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

The Benelux Association for the Study of Art, Culture, and the Environment (BASCE) is a platform for all those who are actively engaged in ecocriticism to discuss their various endeavours with peers from different disciplines and an array of intellectual, creative, or activist pursuits.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

In the 60s and 70s, Black Power groups were also active in the Kingdom of the Netherlands. This is what PhD candidate Debby Esmeé de Vlugt has discovered.

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

On Friday 23 June, the Austrian Studies Fund was established with a festive gathering in the Faculty Club. This fund is the successor of the Austrian Studies Foundation and will continue and expand the program of activities of the Central European Studies chair at Leiden University, which was established…

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

On the following page you can find an overview of all courses provided by the Department of Economics.

We offer a broad and diverse amount of courses. Below, you will find all the information about the courses offered by the Department of Business Sciences. If you click on a course, you will be redirected to the course guide.