2,562 search results for “paddy 1492 1990 disease worked” in the Public website
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
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A novel biofilm for skin barrier repair of patients with atopic eczema
Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…
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Novel receptor concepts
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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Martin Giera
Assistant Professor at the Metabolomics group, LUMC, The Nederlands
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Louise Jawerth Lab
Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.
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Therapeutic Immunomodulation
The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Biotherapeutic Delivery
The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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LUF Children’s Fund
Those who look ahead can see we build the future together.
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Sylvia van Beugen wins ARPH Best Thesis Award
During the 7th annual meeting of the Association for Researchers in Psychology and Health (ARPH) Sylvia van Beugen, from the Health, Medical and Neuropsychology unit, was awarded with the ’Best PhD Thesis Award’ for her dissertation ‘Psychodermatology 2.0: Towards improved assessment and effective digital…
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transition? Multiple Interests in Contexts of Education, Leisure and Work
The overall aim of the project is to investigate interests and their development over time in a daily life context, with particular attention for the transition from late secondary to post secondary education, and from late post secondary education to early career.
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LION Image Awards
On 15 January, the winner of the famed LION Image Award will be announced. Submissions ranged from the famous 3d printed microboat to an eerily abstract graph depicting a Majorana fermion.
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Rachel Doherty wins LION Image Award with famed Microboat image
The annual LION Image award goes to the 30 micrometer long 3D printed microboat image that went viral earlier in October 2020, submitted by Rachel Doherty of the Daniela Kraft lab.
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Mechanistic insights into microRNA-based gene therapy for Huntington disease
PhD defence
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Producing new plants without sowing
Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.
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non-linguistic control mechanisms in bilinguals with neurodegenerative diseases
Lecture, LACG Meetings
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Tentoonstelling: Het onvertelde Caribische verhaal
Het zichtbaar maken van ongeschreven verhalen van inheemse culturen en volken van de Cariben. Dat doet de tentoonstelling ‘Caribbean Ties’ in de Oude UB.
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Soil samples show impact of Columbus's arrival
After Columbus landed on the island of Hispaniola (present-day Haiti and the Dominican Republic), the farming culture of the indigenous people quickly disappeared. This has been demonstrated by Leiden archaeologists and colleagues from other universities on the basis of soil research. Publication in…
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Improving the treatment of pathogenic fungi. ‘The process is working, but not that well…’
Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…
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Effectiveness of programs at lower VET aiming at continuing education or work
The overall aim of the project is to investigate effective ways to strengthen vocational identity of at-risk adolescents in order to contribute to a successful transition from late secondary to post secondary lower vocational education or to work.
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Towards a working model of industry and higher education collaboration in enhancing engineers’ soft skills for better employability
The discussion on employability of higher education graduates has been around for several years, with more emphasis in the 21st century. Yet, universities are still challenged in the pursuit of providing work-ready graduates who can meet industry expectations.
- Borophene for Mutationally Preserved Geno-sensing of Sexually Transmitted Disease
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Hybrid working seems to be working
‘It is OK for employees to work flexibly, as long as they spend 40 hours in the office’, said Elon Musk in June 2022. Are we back where we started now that the pandemic is over? What is needed to make flexibility prosper? Helen Pluut is researcher in Organizational Behaviour at Leiden University and…
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The LeiCNS-PK3.0 model development and applications: Healthy-to- diseased CNS pharmacokinetic translation
PhD defence
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Lecture Series | Novel approaches to delay ageing and age-related diseases
Lecture, Lecture part of a series
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appointed professor of Computational Linguistics: 'If you know how systems work, you can better assess their limitations'
ChatGPT, translation machines and bots: for Carole Tiberius, they are a piece of cake. On 1 January, she was appointed professor of Computational Linguistics. 'There ae two elements to the field: computer science and linguistics.'
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Unemployment Replacement Rates Dataset
The unemployment replacement rate data set, assembled by Olaf Van Vliet & Koen Caminada (version 1, January 2012), provides data on unemployment benefit schemes in 34 welfare states from the 1970s until 2009. The current data set includes all 27 member states of the European Union and 7 non-EU OECD…
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in the context of Dutch primary school teachers that collaborate and work together
Reflective dialogue is an effective instrument for professional learning of teachers. This research considers the characteristics, development, stimulating and limiting conditions for reflective dialogues in the context of Dutch primary school teachers who collaborate and learn together. The goal is…
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CANCELLED: Disease and Violence in Shift from Omurano to Urarina on the Urituyacu River in Peru
Lecture, Language & the Human Past Lecture Series
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These eleven Leiden Science researchers are among the most highly cited
Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Archaeologists in action: stories from the field
During the summer, staff of the Faculty of Archaeology travel to all parts of the world, initiating or joining fieldwork projects. Read some of their stories here!
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A quick call with Nadine Akkerman about the Annie Romein-Verschoor Lecture: ‘I feel a connection with Annie’
Each year on or around International Women’s Day, the university hosts the Annie Romein-Verschoor Lecture. You are welcome to attend − even if you wouldn't call yourself a feminist, says professor and organiser Nadine Akkerman. ‘You get the best discussions with a diverse audience.’
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Psychological health and self-management of people with chronic kidney disease
PhD defence
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data-based dynamic modeling to cell-cell signaling and infectious disease spreading
PhD defence
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Discover our Perspectives on the Past
The Faculty of Archaeology proudly presents the research brochure Perspectives on the Past, featuring passionate, dedicated researchers introducing a dazzling scala of research topics: from present-day traditional knowledge in Africa to the power of glue in Palaeolithic Europe. In addition to these…
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PhD candidates in their own words
The Data Science Research Programme at Leiden University combines data science with PhD projects in a wide range of disciplines. The programme has been running for over two years, and is producing the first astonishing results. A number of PhD candidates talk about their experiences and research bel…
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Why Leiden University?
The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…
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Africa reconsidered
If you follow the western media, you are likely to think of ‘Africa’ as the continent of origin of desperate migrants, a continent of hunger and disease and a breeding ground for international terrorism. But if you want to see the bigger picture, you should look no further than the African Studies scholars…
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Research
The Faculties of Leiden University have developed several themes for research cooperation between Leiden University and its Indonesian partners.
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Urbanization in Indonesia and Its Impact on Non-communicable Diseases
PhD defence
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closer look: Non-invasive tools for in-depth characterisation of vulvar diseases
PhD defence
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in acute myocardial infarction and the assessment of valvular heart disease
PhD defence
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elderly in clinical trials: how to define preclinical Alzheimer’s Disease for clinical trial participation
PhD defence
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Targeting autoimmunity in renal diseases: focus on neutrophil extracellular traps and autoreactive B-cells
PhD defence