The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Decision support tool for cell therapy commercialization and business development

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.

The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

How humans and rats cohabit the cityscape and what consequences this has for both sides of the conflict?

An overview of research projects at the Predictive Pharmacology group.

‘Ordinary citizens’ are featuring more prominently in foreign policies which has already resulted in some unexpected outcomes such as Brexit. Jan Melissen, Senior Fellow at the Institute of Security and Global Affairs (ISGA) conducts research into the societisation of diplomacy. He is interested in…

PhD defence

LeidenGlobal Workshop

There are around 300,000 people in the Netherlands who donate blood on a regular basis. Women can give blood up to three times a year and men up to five times, resulting in approximately one million blood donations each year. Patients that receive this donated blood are already in a vulnerable condition,…

Theft, prostitution, fortune-telling or murder. Historian Manon van der Heijden and a group of students are researching court records from The Hague from 1600 to 1800. They are tracing crimes and offenders and shedding new light on The Hague’s Gevangenpoort (or Prison Gate). Among their many discoveries…

This 48-month project is to contribute to a solid, accessible, domestically owned knowledge base for people-centred interventions aimed at strengthening access to justice in Libya (A2JiL), and to disseminate such knowledge among stakeholders, enhancing awareness and the capabilities required to provide…

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…

For his PhD, historian and army major Dion Landstra researched the effectiveness of observers in peace operations in the Balkans between 1991 and 1995. What risks are acceptable for bringing about and maintaining peace? Landstra will defend his PhD on 28 September.

Street theatre, drama, poetry and a lot of science: Leiden's Rapenburg was the backdrop for the fifth Night of Art and Knowledge on Saturday 16 September. Many University buildings - from the Observatory to the Hortus - opened their doors to artists, scientists and a public curious to know more.

Paul van Trigt and Anna Derksen, both researchers in the project 'Rethinking Disability', received grants for research abroad.

Anyone who knows Aris Politopoulos will be aware of his passion for teaching. Almost winning the Leiden University Teaching Award in 2020, he is known for his use of digital tools to improve his classes. Now he has been accepted to the Leiden Teacher’s Academy. ‘Here I can meet people with innovative…

Tuberculosis bacteria and other intracellular pathogens use cells of our immune system as Trojan horses to spread into tissues. Annemarie Meijer, professor of immunobiology, explains how research into innate defence mechanisms using zebrafish inspires novel strategies for infectious disease treatmen…

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

The central aim is to systematically study differences in crime patterns and social control between migrants and non-migrants in early modern Frankfurt am Main.

For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food. They found…

From colonial times through to the present day, large numbers of Javanese have left their homes to settle in other parts of Indonesia or much further afield. Frequently this dispersion was forced, often with traumatic results.

Our research deals with the deep history of Europe and Eurasia, from the inception of farming up until the beginning of the Roman Period. This was a period in which key developments took place that had a profound impact on European landscapes and society until the present day. Our research and teaching…

WIIS-Netherlands (WIIS-NL) is an affiliate of WIIS Global. WIIS-NL subscribers include: professionals, civil servants, academics, NGOs, employees of international bodies and organizations, embassy staff, politicians, students, and interested members of the general public. The Chapter’s base is Leiden…

We explore the particle physics and quantum world at the time of the big bang.

LIACS is partner in the project 'Stereotyping in Computer Science.' The project is a collaboration between multiple universities and the Dutch national expert organization on girls/women and science/technology (VHTO), which will investigate the stereotypes that children hold about computer scientist…

The research that is united in the Liveable Planet programme, touches upon a wide range of aspects of human life. The goal is to deepen and expand the scope and to connect more researchers. The following case studies are examples of current research projects.

This dissertations studies state-society relations in 1930s Turkey, focusing on the anti-veiling campaigns in the mid-1930s and aiming to understand the ways in which the Kemalist policies were received, interpreted, negotiated, compromised and/or resisted by various actors in the provinces.

Wilke Geurds graduated from the Visual Ethnography master's programme last year with her intimate and vulnerable documentary 'F*ck Endo. More than just menstrual pain.'.

Lecture, Research Seminar Europe 1000-1800

PhD defence

In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…

The Aernout van Lynden Global Citizenship Award award is a recognition given by the LUC community. Each year a student who has demonstrated the qualities of active engagement, responsive and responsible participation in civic and/or community building, within and/or beyond LUC is presented with the…

Can you talk passionately for three minutes about your science or medical research?If the answer's 'Yes', sign up for the Leiden qualifying round of the FameLab international science competition. Registration is now open.

In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.

What is the effect of pesticides, fertilizers or plastic on water quality? And how do wind and rain affect the data? These are just some of the things that Leiden environmental scientists study in the 32 ditches of the Living Lab.

Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'