The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

What does it mean to eat healthily and responsibly? This question is gaining a new urgency now that in many countries undernourishment is being overtaken by diseases of affluence, such as obesity, and we are also becoming more aware of the environmental impact of our eating habits. It’s time to take…

The Institute of Criminal Law and Criminology conducts extensive research on imprisonment. Sending a person to prison is the most severe form of punishment that can be applied in the criminal justice systems of European countries. In most countries, the number of prisoners has risen in recent decades.…

What is the role of auxin in the initiation and process of somatic embryogenesis?

Franc Weerwind studied Public Administration at Leiden University from 1986 to 1992. Right now, mr. Weerwind is the mayor of the municipality of Almere. The editors of Leidraad, the alumni magazine of the university, had a talk with him in context of the recurring ‘workplace’ section in the magazine…

On Friday 23 June, the Austrian Studies Fund was established with a festive gathering in the Faculty Club. This fund is the successor of the Austrian Studies Foundation and will continue and expand the program of activities of the Central European Studies chair at Leiden University, which was established…

On the occasion of the Women & Girls in Science Day, BBC Science Focus Magazine highlighted 6 prominent female chemists. Among them is Leiden professor Ewine van Dishoeck: 'Astrochemist investigating the building blocks of life'.

Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

Heart failure is a major health care problem with high mortality.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

JUSTREMIT is an ERC-funded project that brings together political theory, ethnography, and security studies in an interdisciplinary study of remittances and global justice.

Together with patient representatives, clinician-researchers from Radboucumc (Internal Medicine) Amsterdam UMC and researchers from Leiden University (Andrea Evers and Henriët van Middendorp) have received the Medical Inspirator Prize 2019 of The Netherlands Organisation for Health Research and Development…

What is the role of cell wall-deficiency in the persistence of tuberculosis?

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

Psychiatrists in Morocco can't ignore Islam. Driss Moussaoui was one of the first modern psychiatrists in this North African country. He delivered the LUCIS annual lecture on 12 April.

Cities, Migration and Global Interdependence focuses on inequality in all its forms. You will approach this subject from an intersectional perspective. Since categories of power and identity are always intertwined, the courses in the programme reflect this reality. This means you will study how societies…

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Which plant leaf characteristics are involved in thrips resistance in tomato?

This is an Erasmus+ International Credit Mobility project of Leiden Law School with University of Sarajevo in Bosnia Herzegovina.

Anybody can imagine how difficult it is to read a 2000 years old text for the first time. It is almost inevitable that at first mistakes are made in deciphering and interpretation. This is why revision and correction of published texts play an important role within Papyrology.

Update : March 2020 Director: Professor Dr Harco Willems (KU Leuven), co-director Dr Marleen De Meyer (KU Leuven & NVIC)

This synthesis brings together strands developed in the four studies, sets out memories of the Revolt and presents the Low Countries as a case study.

Why did 'character', 'habit', and 'virtue' serve as key terms in late 19th and early 20th-century scholarly correspondences, biographies, and obituaries? Why did scholars around 1900 display so much interest in the working habits and character traits of what they called the 'scholarly self'?

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Promotor: S.M. Verduyn Lunel

A multi-disciplinary approach to past lifestyles and cultural practices

Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?

Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

How do mycobacteria subvert the defenses of host immune cells?

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

This edited volume by Jeff Fynn-Paul pushes forward the debate on the role of entrepreneurs in making war and building states in Europe and the Ottoman Empire.

On 1 October 2019 the Hazelhoff Centre for Financial law hosted its 19th guest lecture starring Paul Sharma, managing director at Alvarez & Marsal and co-head of the European Financial Industry Regulatory Advisory Services practices.

Sylvia van Beugen has won the Herman Musaph Literature award 2016 for the best publication about psychodermatology. Her publication describes the importance of body awareness in chronic skin conditions, such as psoriasis.