3,244 search results for “paul 1991 1990 disease worden” in the Public website
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Attacking tuberculosis bacteria: an interview with Mónica Varela
This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.
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Osteoarchaeologist Maia Casna interviewed on a podcast
PhD candidate Maia Casna was a guest on the new episode of the Wetenschappelijke Wezens podcast. In it, Maia discusses her research on urbanisation and respiratory diseases while uncovering the intricacies of studying the human past and bones.
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IBL Spotlight - Development and Disease
Lecture
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Tackling chronic respiratory disease in low-resource settings
PhD defence
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Narrating Queer Identities: Politics of Sexuality and Identity Construction in the Novels of James Purdy
In my research I am concerned with the possibility of a politics of sexuality without reverting to identitarian conceptions of sexuality. In a reading of the work of the American author James Purdy, I propose to move towards a politicizing of the concept of narrative identity as developed by the French…
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Tatiana Afanassjewa public lectures about physics
The Tatiana Afanassjewa-lecture series is a series of public talks in Dutch by Leiden physicists on wednesday evenings, intended for everyone with an interest in physics.
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Older Publications
Overview of the publications of the department of Industrial Ecology (1982-2015)
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Key Issues in Historical Theory
This book addresses the definition of history and how people are influenced by it.
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Ronsard and Du Bartas in Early Modern Europe
In the Brill series Intersections a new volume has been published, entitled Ronsard and Du Bartas in Early Modern Europe.
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Van der Heijden Chair Social Justice
On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.
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Hermeneutics and the Humanities
Hermeneutics and the Humanities: Dialogues with Hans-Georg Gadamer / Hermeneutik und die Geisteswissenschaften: Im Dialog mit Hans-Georg Gadamer
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Early Christian Encounters with Town and Countryside
Early Christian Encounters with Town and Countryside - Essays on the Urban and Rural Worlds of Early Christianity.
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The Rise and Decline of an Iberian Bourgeoisie
The Rise and Decline of an Iberian Bourgeoisie is one of the first long-term studies in English of an Iberian town during the late medieval crisis. Focusing on the Catalonian city of Manresa, Jeff Fynn-Paul expertly integrates Iberian historiography with European narratives to place the city's social,…
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Digiuseppe & Poast, ‘Arms versus Democratic Allies’
In theory, states can gain security by acquiring internal arms or external allies. Yet the empirical literature offers mixed findings: some studies find arms and allies to be substitutes, while others find them to be complements. Political scientists Matthew Digiuseppe (Leiden University) and Paul Poast…
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Family, Work and Household in Late Medieval Iberia
Family, Work, and Household presents the social and occupational life of a late medieval Iberian town in rich, unprecedented detail. The book combines a diachronic study of two regionally prominent families—one knightly and one mercantile—with a detailed cross-sectional urban study of household and…
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Andrei Poama for PLOS ONE: Does suffering suffice?
Does suffering suffice? Andrei Poama, Assistant Professor at Leiden University, and Paul C. Bauer, research fellow at the Mannheim Centre for European Social Research, did an experimental assessment of desert retributivism. Their resulsts were published on April 20 on PLOS ONE.
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Slaving Zones. Cultural Identities, Ideologies, and Institutions in the Evolution of Global Slavery
In Slaving Zones: Cultural Identities, Ideologies, and Institutions in the Evolution of Global Slavery, fourteen authors—including both world-leading and emerging historians of slavery—engage with the ‘Slaving Zones’ theory.
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Writing the History of the Humanities: Questions, Themes, and Approaches
What are the humanities? As the cluster of disciplines historically grouped together as “humanities” has grown and diversified to include media studies and digital studies alongside philosophy, art history and musicology to name a few, the need to clearly define the field is pertinent.
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Data Analytics and Management
Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Agrobacterium-mediated protein therapy for genome editing
Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?
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Chilean Transition to Democracy, from 1990 to 2022 Plebiscite: Recent Historical Analysis in Comparative Perspective
Lecture, MAIR Seminar
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Publish or Perish: Religious Zaydi publishers in Yemen during the 1990s
Lecture, LUCIS What's New?! Series
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Frank Schaftenaar
Science
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Programme structure
The master's specialisation Health and Medical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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Onzekerheid bij Professionals in Wijkteams
De decentralisaties van de zorg aan langdurig zieken en ouderen, jeugdzorg, en werk en inkomen die vanaf 2015 zijn doorgevoerd in Nederland hebben geleid tot een transitie van een centraal naar een lokaal stelsel van zorg en welzijn. Deze transitie beoogt zorg en ondersteuning dichter bij de inwoners…
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Metabolomics and Analytics Centre
The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…
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Research with animals
At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.
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Reducing the chronic disease burden in China
PhD defence
- Leiden Academic Centre for Drug Research
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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ADAPTED
The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…
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Noord-Brabantse Oudheden
C.R. Hermans (2012). Facsimile-editie van Noordbrabants Oudheden aangevuld met enkele Archeologische Mengelwerken.
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Europese productnormen en privaatrechtelijke normstelling
On 10 June 2020, Gitta Veldt defended her thesis 'Europese productnormen en privaatrechtelijke normstelling'. The doctoral research was supervised by Prof. H.J. Snijders.
- Van Onzichtbaar naar Zichtbaar / From Invisible to Visible
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(Vorsten)graven in brons- en ijzertijd
Lecture
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Hermen Overkleeft wins the 2015 Jeremy Knowles Award
Prof. Hermen Overkleeft has been awarded the 2015 Jeremy Knowles Award of the Royal Society of Chemistry for his innovative and insightful development of activity-based protein probes for the imaging and identification of enzymes in health and disease.
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'Migraine requires a gender-specific approach'
Migraine is a brain disease. If it were simple, we would have solved it already'. That is the title of the inaugural lecture delivered by Professor of Neurology Gisela Terwindt on Friday 3 June. In her speech she emphasises the importance of research into the differences between women and men with m…
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Revolutionizing plant protection strategies: Ding lab receives 2.4M grant to investigate plant immunity
Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…
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Publications
The NVIC has published a series of scholarly publications in Arabic and several European languages.
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Mechanistic Early Phase Clinical Pharmacology Studies with Disease
PhD defence
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The synthesis of chemical tools for studying sphingolipid metabolism
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.