2,375 search results for “paddy 1492 1992 disease works” in the Public website
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Cardiovascular disease burden in thoracic aortopathy
PhD defence
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Predicting Outcomes in Patients with Kidney Disease
PhD defence
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Maximal Systolic Acceleration in atherosclerotic vascular disease
PhD defence
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Adult weight change and cardiometabolic disease
PhD defence
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Big data on a small scale
Mirjam van Reisen favours big data built up from local inputs in developing countries and suitable for local use. The new Professor of Computing for Society at Leiden's Faculty of Science connects data science with development sociology. Inaugural lecture 10 March.
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HR Excellence in research - Working at Leiden University
To recruit, enthuse and give talent from home and abroad room to grow, Leiden University has developed good HR policies for researchers.
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Collaboration starts quest for new antibiotics through NWO fund
Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.
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Fundamental Research in Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Immunotherapy to limit atherosclerosis
Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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The scientists behind LED3
LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.
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Programme structure
The research master's specialisation Clinical and Health Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Predictive pharmacology
The aim of this research area is to be able to predict human drug response on the basis of mathematical models that are developed using preclinical experiments and prior knowledge.
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Host-Microbe Interactions in Microbial Sciences
Microbial Sciences' contribution to the Host-Microbe Interactions research theme is to investigate how beneficial or disease-causing microbes associate and interact with their host.
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Reading the Dental record
A dental anthropological approach to foodways, health and disease, and crafting in the pre-Columbian Caribbean.
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
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Conceptualisation of disease resolution in rheumathoid arthritis
PhD defence
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Inflammatory Bowel Disease in Older Patients
PhD defence
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Master Projects
Master projects are available in
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GRIPonMASH
GRIPonMASH will address the unmet public health need of reducing disease burden and comorbidities associated with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD).
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Centre for Interdisciplinary Genome Research
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.
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SDS-PAGE at the nanoscale: A nanorecorder for single molecule protein sequencing with graphene
Can we find new chemical and biological sensing routes on the edge and surface of graphene to improve the potential of graphene to act as a sensor?
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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High-Throughput Metabolomics
Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics
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BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
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Layers of dental tartar
Bacteria in the teeth tell us a lot about nutrition and disease in our ancestors. It also tells us more about the immune system. This provides clues for treating modern diseases and allergies. For a long time archaeologists were irritated by tartar on the teeth of excavated skulls. They thought that…
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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Stevin Prize winner Andrea Evers: 'This award is for the whole team'
Health psychologist Andrea Evers has won the Stevin Prize – alongside the Spinoza Prize, the highest scientific award in the Netherlands. Evers: 'It’s also a prize for our whole team and our many contacts within and outside the University.’
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Amanda Foks receives Dekker grant from Dutch Hartstichting
Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.
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The Mastermind approach to brain research
The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach. ‘In effect, it's like playing Mastermind.’ Inaugural lecture on 22 March.
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Sectoral Income Inequality Dataset
The Leiden LIS Sectoral Income Inequality Dataset, assembled by Chen Wang, Stefan Thewissen and Olaf van Vliet (Version 1.1, March 2014), contains information on multiple indicators of earnings inequality and employment within 9 sectors and 12 subsectors, drawing upon micro data from Luxembourg Income…
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Collaborative and effective drug development
There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…
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Professional development of VET teachers in the context of work placement
This project focuses on vocational teachers’ professional development in work placement. Teachers’ learning motivation, learning experience and learning outcomes within work placement will be explored in depth.
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Cognitive Uncertainty and Employees’ Daily Innovative Work Behavior: The Moderating Role of Ambidextrous Leadership
Bernard Bernards examines constraints on innovation by focusing on cognitive uncertainty as a personal state that may affect innovative work behavior.
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Targeting Inter-Organ Cross-Talk in Cardiometabolic Diseases
PhD defence
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Research lines
Current research at the Skin Barrier and Vaccination group.
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Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges
On 9 June 2020, Maral Darouei defended her thesis 'Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges'. The doctoral research was supervised by Prof. J.I. van der Rest.
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Another successful collaboration between Leiden Law School and LUMC
Researchers from Leiden Law School and the LUMC have received a grant for a joint research project. They will be looking into ways in which caregivers and patients can work together to come to a better decision.
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'I have always worked for a better world. Here at Biology we do the same'
The new institute manager of the IBL studied biology for six months, but went in a completely different direction: development cooperation and the financial sector. Three decades later, Resi Janssen is making a radical career switch. Or isn’t she? 'In ten years’ time I want IBL to be in a new, sustainable…
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Influence of dissociation on the neural correlates of Emotional Working Memory in Borderline Personality Disorder
How do dissociative states affect the ability to suppress emotional distraction (in the context of a working memory task) in patients with Borderline Personality Disorder?
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Professional learning of vocational teachers in the context of work placement
Work placement as a professional development programme for vocational teachers has been widely implemented. This dissertation provides insight into vocational teachers’ learning process in this programme within Chinese vocational education.
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Miranda van Eck inaugural lecture: detergent tablets for clean, fat-free blood vessels
In her inaugural lecture on 11 September, Miranda van Eck, Professor of Cardiovascular and Metabolic Therapeutics, addressed her research related to developing medications to keep our blood vessels clean.
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Leiden researchers join forces against tuberculosis
About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…