4,141 search results for “paul 1521 1990 disease worked” in the Public website
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Career and development - Working at Leiden University
If you have the ambition to continuously develop and grow in your work, then Leiden University is an attractive employer for you.
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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From Find Scatters to Early Hominid Behaviour
A Study of Middle Palaeolithic Riverside Settlements at Maastricht-Belvédère (The Netherlands).
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Beyond the Site
The Saalian archaeological record at Maastricht-Belvédère (the Netherlands).
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Asylum Policy, Boat People and Political Discourse - Boats, Votes and Asylum in Australia and Italy
This book compares the policies of Australia and Italy towards boat people who have arrived in the two countries since the early 1990s.
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Sustainable campus
Leiden University is working on a green, circular campus, with a significant reduction in energy consumption by 2050 as its goal, as elaborated in the Route Map Energy Transition Buildings, published in 2022.
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William of Orange Medal
Since 1990 Leiden University has awarded the William of Orange medal to individuals of eminent national or international social standing.
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Postmaterialism and Socioeconomic Status Impact in the Chilean Voting Behavior
This paper describes the development process of voting behavior in Chile; particularly the relationship between the class voting theory and the theory of cultural post-materialist vote is investigated. This research deals with Chile as a case study, a developing country with a relatively stable democracy…
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Nominalization: the view from syntactic approaches to word formation
Lecture, LUCL Colloquium - Series '24/'25
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Life Course
As a result of an increased life expectancy, more people suffer from chronic diseases and discomfort. Elderly patients may have multiple diseases simultaneously, with concomitant multiple medications.
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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How these young researchers are preparing for their first scientific conference
Three Psychology students will present a poster of their thesis research on Alzheimer’s and dementia at the international conference AAIC Neuroscience Next. ‘I remind myself to recognise - without fear or shame - when I don't know something.’
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Lessons from Rare Diseases
PhD defence
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Leiden University scientists - Working at Leiden University
Nobody is better qualified to tell you what it is like to work at Leiden University than the employees themselves. Watch the videos and meet your future colleagues. They will be happy to share their experiences with you.
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About the program
In 2020, Leiden University launched its stimulated interdisciplinary programs, including one focused on regenerative medicine.
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Next Generation ImmunoDermatology project
The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile the immune-mediated inflammatory diseases: i) atopic dermatitis (AD), ii) cutaneous lupus erythematosus (CLE) iii) chronic spontaneous urticaria (CSU) iv) hidradenitis suppurativa (HS) v)…
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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The World of the Fullo. Work, Economy, and Society in Roman Italy
The World of the Fullo takes a detailed look at the fullers, craftsmen who dealt with high-quality garments, of Roman Italy. Analyzing the social and economic worlds in which the fullers lived and worked, it tells the story of their economic circumstances, the way they organized their workshops, the…
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Why don't drugs make it to the market?
How can we extend the drug residence time to combat diseases more effectively?
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Aging and Immunity
The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.
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Vertebrate automated screening technology (VAST)
How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Chemical biology of sphingolipids: fundamental studies and clinical applications
Overkleeft
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About Leiden University - Working at Leiden University
As far back as 1575, Leiden University researchers have been leaving their mark on the world.
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CoSTREAM: Understanding Stroke and Alzheimer
The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Rational Design of Athero-Protective Vaccines; Novel Vaccine Formulations and Alternative Routes of Administration
Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.
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The Hague International Space Resources Governance Working Group
The development of space resource activities is happening now. In the absence of a clear framework to govern these activities, there is a need to examine the concepts that are being discussed in order to ensure that they meet existing treaty obligations regarding on-orbit operations and space resource…
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Translations of Greek Tragedy in the Work of Ezra Pound
Turning the tables on the misconception that Ezra Pound knew little Greek, this volume looks at his work translating Greek tragedy and considers how influential this was for his later writing.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Osteoarchaeologist Maia Casna interviewed on a podcast
PhD candidate Maia Casna was a guest on the new episode of the Wetenschappelijke Wezens podcast. In it, Maia discusses her research on urbanisation and respiratory diseases while uncovering the intricacies of studying the human past and bones.
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Nose of E. coli zips open and shut
PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.
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Attacking tuberculosis bacteria: an interview with Mónica Varela
This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.
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Cell architecture and pathways for parallel secretion in the filamentous fungus Aspergillus niger
Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
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IBL Spotlight - Development and Disease
Lecture
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Tatiana Afanassjewa public lectures about physics
The Tatiana Afanassjewa-lecture series is a series of public talks in Dutch by Leiden physicists on wednesday evenings, intended for everyone with an interest in physics.
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Narrating Queer Identities: Politics of Sexuality and Identity Construction in the Novels of James Purdy
In my research I am concerned with the possibility of a politics of sexuality without reverting to identitarian conceptions of sexuality. In a reading of the work of the American author James Purdy, I propose to move towards a politicizing of the concept of narrative identity as developed by the French…
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Law and peace in the work of Hans Kelsen
Law and peace in the work of Hans Kelsen. A re-evaluation of Kelsen’s legal philosophy: legal pacifism as tacit meaning of his Pure Theory of Law
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Single-cell mechanics for disease biology and pharmacology
PhD defence
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Key Issues in Historical Theory
This book addresses the definition of history and how people are influenced by it.
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Hermeneutics and the Humanities
Hermeneutics and the Humanities: Dialogues with Hans-Georg Gadamer / Hermeneutik und die Geisteswissenschaften: Im Dialog mit Hans-Georg Gadamer
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Early Christian Encounters with Town and Countryside
Early Christian Encounters with Town and Countryside - Essays on the Urban and Rural Worlds of Early Christianity.
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Ronsard and Du Bartas in Early Modern Europe
In the Brill series Intersections a new volume has been published, entitled Ronsard and Du Bartas in Early Modern Europe.
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Andrei Poama for PLOS ONE: Does suffering suffice?
Does suffering suffice? Andrei Poama, Assistant Professor at Leiden University, and Paul C. Bauer, research fellow at the Mannheim Centre for European Social Research, did an experimental assessment of desert retributivism. Their resulsts were published on April 20 on PLOS ONE.
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Van der Heijden Chair Social Justice
On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.
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Writing the History of the Humanities: Questions, Themes, and Approaches
What are the humanities? As the cluster of disciplines historically grouped together as “humanities” has grown and diversified to include media studies and digital studies alongside philosophy, art history and musicology to name a few, the need to clearly define the field is pertinent.
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Slaving Zones. Cultural Identities, Ideologies, and Institutions in the Evolution of Global Slavery
In Slaving Zones: Cultural Identities, Ideologies, and Institutions in the Evolution of Global Slavery, fourteen authors—including both world-leading and emerging historians of slavery—engage with the ‘Slaving Zones’ theory.