Dr. Jessica Kiefte-de Jong and Dr. Thijs Bosker, both Assistant Professors at LUC, have been awarded by The Leiden University Fund (LUF).

How can we extend the drug residence time to combat diseases more effectively?

How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Overkleeft

Overview of the publications of the department of Environmental Biology (1972-2015)

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…

This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.

PhD defence

How do macrophages and neutrophils contribute to metastatic onset?

This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.

What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?

Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

This summer postdoctoral researcher Mónica Varela from the Institute of Biology Leiden was awarded a Veni grant from the Dutch Research Council (NWO). Six questions about her project and hopes for the future.

PhD candidate Maia Casna was a guest on the new episode of the Wetenschappelijke Wezens podcast. In it, Maia discusses her research on urbanisation and respiratory diseases while uncovering the intricacies of studying the human past and bones.

The proposed project evaluates how the vulnerability of migrant men and women was constructed in political, public and media discourses, and how differences in the constructed vulnerability influenced the decision to migrate, the migration process, and the subsequent settlement process.

The WIIS network is about the advancement of women's leadership. To best accomplish our mission, we need subscribers like you. As a dues-paying subscribers of Women In International Security (WIIS), you will have the ability to contribute to the WIIS Blog, receive WIIS this Week, access and post to…

Lecture

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Leiden researchers study the extent to which Asian citizens can invoke the rights that they have on paper. This knowledge helps them advise the different levels of government and NGOs on how to improve the lot of poor citizens in particular.

PhD defence

Our subscribers have written several publications about international security issues.

Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Conference

Machine Learning is becoming a more and more substantial technology for industry.

Is translocation of nucleases possible via Agrobacterium T4SS and is it efficient enough for mutagenesis?

Lecture, MAIR Seminar

Lecture, LUCIS What's New?! Series

The master's specialisation Health and Medical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

The ambition of the Metabolomics and Analytics Centre led by Thomas Hankemeier is to develop innovative analytical strategies for metabolomics-driven health monitoring and systems biology studies. Understanding the intricate balance between health, disease and adaptation to challenges relies on the…

At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.

PhD defence

Conference

Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Control of infectious diseases poses continuous challenges for human health.

The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

Ariadne Schmidt, Isabelle Devos and Julie de Groot provide you with refreshing insights concerning the study on urban singles in the period between 1200 and 1900.