Inspired by a critical reconsideration of current monolithic approaches to the study of Greek religion, this book argues that ancient Greeks displayed a disquieting capacity to validate two (or more) dissonant, if not contradictory, representations of the divine world in a complementary rather than…

Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.

In this article, Ben de Jong, research fellow at the Institute of Security and Global Affairs, examines the relationship between double agents and their handlers.

Representing Japanese Colonial 'Heritage' in Taiwan

This paper aims to understand the most common underlying problems causing strategic surprise in the context of the European Union.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

The project ‘Founding an Inclusive Space’ investigates the histories of various LGBT+ archives in the Netherlands, Germany and the United Kingdom.

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

This project suggests a reconceptualisation of pre- and non-capitalist imperial monetary policy, arguing that the existing literature about imperial financial flows has unnecessarily privileged ideas of largesse and seemingly chaotic monetary distribution. Using the divergent cases of the Roman Empire…

Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.

Family, Work, and Household presents the social and occupational life of a late medieval Iberian town in rich, unprecedented detail. The book combines a diachronic study of two regionally prominent families—one knightly and one mercantile—with a detailed cross-sectional urban study of household and…

It often takes longer for women with heart problems to get the right diagnosis. In her Annie Romein-Verschoor Lecture, Professor Hester den Ruijter will talk about how hormones influence the heart and the importance of medical research that focuses specifically on women.

PhD defence

Postdoc Lucia Bossoni has received an NWO Veni grant to research brain diseases for the next three years. She will work in labs at both the LUMC and the Leiden physics institute.

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…

The rapid advances in imaging technology enable to see inside the body with ever increasing detail.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi

Research projects

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

This research investigates the impact of socioeconomic developments on the physical condition of medieval populations in Holland and Zeeland between AD 1000 and 1600 through the analysis of human skeletal remains from three archaeological sites.

Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

In this top-rated course, you will learn how the European Union prepares and decides on policy, and how policy is transferred to member states and implemented by various authorities. It discusses the challenges of the European multi-level governance structure and the main causes of policy failure or…

On 9 September, in the presence of King Willem Alexander, Secretary of State Sander Dekker presented the Spinoza Prize to four researchers, including two researchers from Leiden: archaeologist Corinne Hofman and physicist Dirk Bouwmeester. In the Nieuwe Kerk in The Hague, they unveiled their plans for…

Α-synuclein, a protein associated with Parkinson’s disease, proves to bind with membranes in a surprisingly efficient way. It confirms scientists’ suspicion of the protein’s leading role in the transmission of neurotransmitters between nerve cells in the brain. Publication in PLoS ONE.

This research project studies the distribution and impact of medieval malaria in the Netherlands.

Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

Leiden heritage expert Sjoerd van der Linde is carrying out research on the heritage of the Caribbean region. This research forms part of the international Nexus 1492 project on the consequences of colonisation for the Americas. ‘We first have to find out what the local population wants.'

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

An overview of research themes and projects at ABS.

The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.

The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.

This dissertation is a study of North Korean art as a site where politics, history, and culture meet.

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

This project intends to provide the required knowledgebase for the design of novel mild intervention protocols to prevent fungal food spoilage.

PhD defence

PhD defence